Vancouver Island First Nation whose ancestors met explorer Capt. Cook sue provinceSony Semiconductor Manufacturing which has the world’s largest global market share in image sensors has shipped more than 20 billion sensors to date, says a top executive at the company. Yoshihiro Yamaguchi, president of Sony Semiconductor Manufacturing, told Japan’s Nikkei newspaper that the company is also building a new plant in Japan’s Kumamoto prefecture. Yamaguchi says that the company hit the 10 billion mark in May 2019, and then in just five years has doubled that figure. He attributes that dramatic jump to the use of its sensors in mobile phones. Not only have the number of mobile phones being produced increase, but each phone also featured multiple cameras. Apple, for example, is believed to be using Sony’s sensors in its cameras. Apple is closing 2024 with a 27.7% smartphone market share, 4.5% more than rival Samsung, according to data from Stocklytics.com. Sony has four facilities in Kyushu, Japan. He says that there are not going to be any major changes at each facility, but “Nagasaki, Oita and Kumamoto are handling 300-millimeter wafers, and Kagoshima is using 200-mm wafers to produce unique devices, mainly analog large-scale integrated circuits.” “In Kyushu, image sensor production is centered in Nagasaki, Kumamoto and Oita. Kumamoto is also producing devices for automotive and other growth areas. Nagasaki and Oita are producing sensors for mobile devices.” Construction has begun on a new factory in Kumamoto prefecture. He says that the new factory will likely first produce image sensors for mobile devices which is the company’s current focus, handling overflow from the factory in Isahaya, Nagasaki prefecture. Beyond mobile devices, Yamaguchi forecasts growth in demand for image sensors coming from areas including in-vehicle devices, smart factories, smart ICT [information and communication technology] cameras, as well as semiconductor laser devices used in peripheral displays and data centers. In February this year, TSMC, Sony Semiconductor Solutions Corporation, DENSO Corporation and Toyota Motor Corporation announced a further investment into Japan Advanced Semiconductor Manufacturing (JASM), TSMC’s majority-owned manufacturing subsidiary in Kumamoto Prefecture, Japan, to build a second fab, which is scheduled to begin operation by the end of the 2027 calendar year. Together with JASM’s first fab, the overall investment in JASM will exceed US$20 billion (A$32.18 billion) with strong support from the Japanese government. “We are progressing smoothly with our evaluation of the process of stacking logic semiconductors made by TSMC and JASM [Japan Advanced Semiconductor Manufacturing, the TSMC subsidiary that operates the Kumamoto plant] to produce finished CMOS image sensors at our facility,” says Yamaguchi. “From the perspective of strengthening the supply chain, having a place nearby that can supply logic chip wafers can offer peace of mind when various risks arise. To prepare for risks, we plan to be in a position where we can receive wafers from JASM at any time.” As ChannelNews reported earlier this year, major Japanese companies including Sony Group and Mitsubishi Electric are outlining plans to spend around A$53.52 billion (5 trillion yen) in semiconductor production before the end of this decade. That figure represents the capital investment from 2021 until 2029 by eight Japanese chipmakers including Sony Group, Mitsubishi Electric, Rohm, Toshiba, Kioxia Holdings, Renesas Electronics, Rapidus and Fuji Electric.

Holy Cross secures 82-46 victory over Regis (MA)

By HILLEL ITALIE NEW YORK (AP) — Even through a year of nonstop news about elections, climate change, protests and the price of eggs, there was still time to read books. Related Articles Hundreds of bookstore staffers receive holiday bonuses from author James Patterson Nikki Giovanni, poet and literary celebrity, has died at 81 Percival Everett, 2024 National Book Award winner, rereads one book often Gift books for 2024: What to give, and what to receive, for all kinds of readers Our critic’s picks: Best mystery fiction books of 2024 U.S. sales held steady according to Circana, which tracks around 85% of the print market, with many choosing the relief of romance, fantasy and romantasy. Some picked up Taylor Swift’s tie-in book to her blockbuster tour, while others sought out literary fiction, celebrity memoirs, political exposes and a close and painful look at a generation hooked on smartphones. Here are 10 notable books published in 2024, in no particular order. Asking about the year’s hottest reads would basically yield a list of the biggest hits in romantasy, the blend of fantasy and romance that has proved so irresistible fans were snapping up expensive “special editions” with decorative covers and sprayed edges. Of the 25 top sellers of 2024, as compiled by Circana, six were by romantasy favorite Sarah J. Maas, including “House of Flame and Shadow,” the third of her “Crescent City” series. Millions read her latest installment about Bryce Quinlan and Hunter Athalar and traced the ever-growing ties of “Maasverse,” the overlapping worlds of “Crescent City” and her other series, “Throne of Glass” and “A Court of Thorns and Roses.” If romantasy is for escape, other books demand we confront. In the bestselling “The Anxious Generation,” social psychologist Jonathan Haidt looks into studies finding that the mental health of young people began to deteriorate in the 2010s, after decades of progress. According to Haidt, the main culprit is right before us: digital screens that have drawn kids away from “play-based” to “phone-based” childhoods. Although some critics challenged his findings, “The Anxious Generation” became a talking point and a catchphrase. Admirers ranged from Oprah Winfrey to Arkansas Gov. Sarah Huckabee, who in a letter to state legislators advocated such “commonsense recommendations” from the book as banning phones in schools and keeping kids off social media until age 16. Bob Woodward books have been an election tradition for decades. “War,” the latest of his highly sourced Washington insider accounts, made news with its allegations that Donald Trump had been in frequent contact with Russian leader Vladimir Putin even while out of office and, while president, had sent Putin sophisticated COVID-19 test machines. Among Woodward’s other scoops: Putin seriously considered using nuclear weapons against Ukraine, and President Joe Biden blamed former President Barack Obama, under whom he served as vice president, for some of the problems with Russia. “Barack never took Putin seriously,” Woodward quoted Biden as saying. Former (and future) first lady Melania Trump, who gives few interviews and rarely discusses her private life, unexpectedly announced she was publishing a memoir: “Melania.” The publisher was unlikely for a former first lady — not one of the major New York houses, but Skyhorse, where authors include such controversial public figures as Woody Allen and Trump cabinet nominee Robert F. Kennedy Jr. And its success was at least a minor surprise. Melania Trump did little publicity for the book, and offered few revelations beyond posting a video expressing support for abortion rights — a break from one of the cornerstones of GOP policy. But “Melania” still sold hundreds of thousands of copies, many in the days following her husband’s election. Taylor Swift was more than a music story in 2024. Like “Melania,” the news about Taylor Swift’s self-published tie-in to her global tour isn’t so much the book itself, but that it exists. And how well it sold. As she did with the “Eras” concert film, Swift bypassed the established industry and worked directly with a distributor: Target offered “The Eras Tour Book” exclusively. According to Circana, the “Eras” book sold more than 800,000 copies just in its opening week, an astonishing number for a publication unavailable through Amazon.com and other traditional retailers. No new book in 2024 had a better debut. Midnight book parties are supposed to be for “Harry Potter” and other fantasy series, but this fall, more than 100 stores stayed open late to welcome one of the year’s literary events: Sally Rooney’s “Intermezzo.” The Irish author’s fourth novel centers on two brothers, their grief over the death of their father, their very different career paths and their very unsettled love lives. “Intermezzo” was also a book about chess: “You have to read a lot of opening theory — that’s the beginning of a game, the first moves,” one of the brothers explains. “And you’re learning all this for what? Just to get an okay position in the middle game and try to play some decent chess. Which most of the time I can’t do anyway.” Lisa Marie Presley had been working on a memoir at the time of her death , in 2023, and daughter Riley Keough had agreed to help her complete it. “From Here to the Great Unknown” is Lisa Marie’s account of her father, Elvis Presley, and the sagas of of her adult life, notably her marriage to Michael Jackson and the death of son Benjamin Keough. To the end, she was haunted by the loss of Elvis, just 42 when he collapsed and died at his Graceland home while young Lisa Marie was asleep. “She would listen to his music alone, if she was drunk, and cry,” Keough, during an interview with Winfrey, said of her mother. Meanwhile, Cher released the first of two planned memoirs titled “Cher” — no further introduction required. Covering her life from birth to the end of the 1970s, she focuses on her ill-fated marriage to Sonny Bono, remembering him as a gifted entertainer and businessman who helped her believe in herself while turning out to be unfaithful, erratic, controlling and so greedy that he kept all the couple’s earnings for himself. Unsure of whether to leave or stay, she consulted a very famous divorcee, Lucille Ball, who reportedly encouraged her: “F— him, you’re the one with the talent.” A trend in recent years is to take famous novels from the past, and remove words or passages that might offend modern readers; an edition of “The Adventures of Huckleberry Finn” cuts the racist language from Mark Twain’s original text. In the most celebrated literary work of 2024, Percival Everett found a different way to take on Twain’s classic — write it from the perspective of the enslaved Jim. “James,” winner of the National Book Award, is a recasting in many ways. Everett suggests to us that the real Jim was nothing like the deferential figure known to millions of readers, but a savvy and learned man who concealed his intelligence from the whites around him, and even from Twain himself. Salman Rushdie’s first National Book Award nomination was for a memoir he wished he had no reason to write. In “Knife,” he recounts in full detail the horrifying attempt on his life in 2022, when an attendee rushed the stage during a literary event in western New York and stabbed him repeatedly, leaving with him a blinded eye and lasting nerve damage, but with a spirit surprisingly intact. “If you had told me that this was going to happen and how would I deal with it, I would not have been very optimistic about my chances,” he told The Associated Press last spring. “I’m still myself, you know, and I don’t feel other than myself. But there’s a little iron in the soul, I think.”Major high street retailer with 130 UK branches to CLOSE popular store for good as shoppers warned ‘all stock must go’Apple halts effort to build iPhone hardware subscription service

Article content Earlier this year, the U.S. National Highway Traffic Safety Administration (NHTSA) opened an investigation into more than three-quarters of a million Jeep Wrangler and Gladiator vehicles from model years 2021 to 2023 to understand the source of reported under-hood fires. Now, some owners are taking Jeep to task over the issue by turning to the American legal system. In a complaint filed south of the border, plaintiffs from states ranging from Kentucky and Tennessee to Oregon and California are seeking unspecified damages and a fix to the alleged defect. Those bringing the suit to court say they would not have bought the models in question, or paid significantly less for them, had they known about such issues. In nine reported incidents with one reported injury, conflagration – ahem, fiery – incidents may have occurred while the vehicles had their ignitions turned off, though some are said to have caught fire whilst running. It is suggested an electrical connector at the power steering pump contributes to the problem. Online searches for dockets and filings tell us this legal challenge is titled ‘Graves et al v. FCA US LLC,’ and was launched on November 7 of this year with the U.S. District Court for the Eastern District of Michigan. Fun fact: it cost a fee of $405 to do so, not counting whatever untold rate is being charged by the phalanx of lawyers listed in the proceeding. The name “Graves” listed in the lawsuit seems to refer one Jeff Graves of California. Interestingly, there is also a historical record of one Robert Graves bringing legal action against Jeep back in 2021 for a litany of complaints about his 2014 Jeep Cherokee. There is nothing to say he is related to the Jeff Graves whose name headlines this latest legal challenge against the brand, but they did both own Jeeps and are both listed in court documents as being from California. (There are, of course, also nearly 40 million people living in California.) The plaintiffs in this case seek to represent a national class of buyers and lessees of the allegedly affected Jeeps in the United States. This lawsuit raises legal claims including a so-called breach of warranty and unjust enrichment for the automaker. Graves et al are looking for remedies including a repair for the alleged defect; restitution; and everyone’s absolute favourite legal ask, damages. Sign up for our newsletter Blind-Spot Monitor and follow our social channels on X , Tiktok and LinkedIn to stay up to date on the latest automotive news, reviews, car culture, and vehicle shopping advice.MtoZ Biolabs Launches High-Sensitivity Quantitative Phosphoproteomics Service to Advance Cutting-Edge Biomedical Research 12-18-2024 11:54 PM CET | Health & Medicine Press release from: ABNewswire MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Quantitative phosphoproteomics service [ https://www.mtoz-biolabs.com/phospho-proteomics.html ] utilizes advanced phosphopeptide enrichment methods combined with high-sensitivity mass spectrometry to accurately quantify and identify phosphoproteins with low abundance and across a wide dynamic range. Since the late 1990s, advancements in mass spectrometry have transformed phosphoprotein research, shifting from qualitative to quantitative analysis. This evolution has made quantitative phosphoproteomics essential for understanding cell signaling, disease mechanisms, and drug discovery. MtoZ Biolabs' quantitative phosphoproteomics service [ https://www.mtoz-biolabs.com/phospho-proteomics.html ] addresses the challenges associated with low-abundance and wide-dynamic-range phosphorylated proteins. By leveraging advanced enrichment techniques such as titanium dioxide (TiO) and immobilized metal affinity chromatography (IMAC), along with targeted antibody-based methods, we ensure comprehensive and precise phosphoproteome analysis. The integration of iTRAQ/TMT labeling technologies further enhances detection sensitivity and quantitative accuracy, enabling in-depth exploration of critical signaling pathways and molecular mechanisms. Technical Principle and Workflow of Quantitative Phosphoproteomics Service at MtoZ Biolabs Mass spectrometry-based phosphoproteomics solutions [ https://www.mtoz-biolabs.com/phospho-proteomics.html ] enable precise analysis of phosphorylation as a key post-translational modification, which adds a phosphate group to proteins, increasing the molecular mass by 79.97 Da. High-resolution mass spectrometry (HRMS) enables precise localization of phosphorylation sites through the detection of mass shifts and fragmentation spectra, supporting both qualitative and quantitative analyses of phosphoproteins. At MtoZ Biolabs, our quantitative phosphoproteomics service leverages HRMS and a streamlined workflow to ensure efficient sample preparation, targeted enrichment, and precise data analysis. The key steps are outlined below: * Sample Preparation - Proteins are extracted from cell, tissue, or body fluid samples using cryogenic lysis, ultrasonic disruption, or chemical lysis to maintain protein integrity. Protein concentration and quality are assessed using methods such as BCA assays or SDS-PAGE to ensure compatibility with downstream enzymatic digestion and analysis. * Digestion and Labeling - Total proteins are enzymatically digested into peptides using trypsin. To facilitate simultaneous quantification of multiple samples, isotopic labeling techniques, such as iTRAQ or TMT, are applied to the peptides. Strict control of reaction conditions, including temperature and pH, ensures high labeling efficiency and peptide stability. * Enrichment of Phosphopeptides - The quantitative phosphoproteomics service addresses the low abundance of phosphoproteins by employing TiO-based or IMAC methods for the selective enrichment of phosphopeptides. For targeted phosphorylation studies, MtoZ Biolabs provides serine/threonine or tyrosine phosphorylation-specific antibody enrichment, enabling precise capture of modified peptides while minimizing nonspecific interactions. * Mass Spectrometry Analysis - Enriched phosphopeptides in this service are analyzed using HRMS platforms. MS1 scans determine peptide precursor masses, while MS2 fragmentation spectra provide accurate localization of phosphorylation sites. Advanced acquisition modes, including dynamic exclusion and multi-stage fragmentation monitoring (MS/MS), enhance data depth and reliability. * Data Analysis - Acquired mass spectrometry data are processed with specialized bioinformatics tools, such as MaxQuant or Proteome Discoverer, to identify phosphoproteins and their modification sites. The MtoZ Biolabs bioinformatics team delivers comprehensive results, including quantitative comparisons, functional enrichment analyses, and detailed pathway network visualizations. Why Choose MtoZ Biolabs? Our primary advantages include: * Optimized Enrichment and Highly Sensitive Detection - Utilizing state-of-the-art phosphoprotein enrichment methodologies combined with highly sensitive mass spectrometric analyses, we enable the precise identification and localization of phosphorylated proteins with accuracy. * Reduced Inter-Sample Variability - Through iTRAQ/TMT labeling technologies, MtoZ Biolabs significantly mitigates variability both within and between samples, thereby ensuring a robust and reliable framework for quantitative phosphoproteomics service. * Enhanced Detection of Low-Abundance Phosphoproteins - Our platform is specifically optimized to detect low-abundance phosphorylated proteins, achieving exceptional sensitivity and comprehensive coverage, thereby facilitating in-depth exploration of critical signaling pathways within complex biological samples. * Support for Broad Dynamic Range Analysis - Quantitative phosphoproteomics service at MtoZ Biolabs is designed to accommodate a broad dynamic range, addressing the diverse and multifaceted research requirements of complex and multi-layered biological systems. * One-Time-Charge - Our pricing is transparent, no hidden fees or additional costs. * High-Data-Quality - Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrates all quantitative phosphoproteomics analysis data, providing clients with a comprehensive data report. Applications MtoZ Biolabs' quantitative phosphoproteomics service is widely applied across various critical areas of biomedical research, including: * Neurodegenerative Diseases - Through in-depth profiling of phosphorylation dynamics within the nervous system, quantitative phosphoproteomics analysis helps uncover the molecular mechanisms underlying neuronal dysfunction and the progression of diseases such as Alzheimer's and Parkinson's. * Mechanisms of Tumorigenesis - Using state-of-the-art phosphoproteomics technologies, MtoZ Biolabs maps signaling pathways and phosphorylation networks in tumor cells. These analyses identify pivotal regulatory factors that drive tumor initiation, growth, and drug resistance, thus laying the groundwork for precision medicine and tailored therapeutic approaches. * Drug Target Identification - With precise quantitative analysis of how drugs influence phosphorylation signaling pathways, this approach facilitates the discovery of disease-associated drug targets. Quantitative phosphoproteomics service also validates the regulatory impacts of drugs on key signaling molecules, providing robust scientific evidence for drug development and therapeutic enhancement. What Could be Included in the Report? * Comprehensive Experimental Details * Materials, Instruments, and Methods * Total Ion Chromatogram & Quality Control Assessment (project-dependent) * Data Analysis, Preprocessing, and Estimation (project-dependent) * Bioinformatics Analysis * Raw Data Files MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced proteomics [ https://www.mtoz-biolabs.com/proteomics.html ], metabolomics [ https://www.mtoz-biolabs.com/metabolomics.html ], and biopharmaceutical analysis [ https://www.mtoz-biolabs.com/biopharmaceuticals.html ] services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Interested in learning more about how our quantitative phosphoproteomics service [ https://www.mtoz-biolabs.com/phospho-proteomics.html ] can enhance your research? Free project evaluation. Media Contact Company Name: MtoZ Biolabs Contact Person: Terry Email:Send Email [ https://www.abnewswire.com/email_contact_us.php?pr=mtoz-biolabs-launches-highsensitivity-quantitative-phosphoproteomics-service-to-advance-cuttingedge-biomedical-research ] Phone: +1-857-362-9535 Address:155 Federal Street Suite 700 City: Boston State: MA Country: United States Website: https://www.mtoz-biolabs.com/ This release was published on openPR.

Egg prices are once again spiraling out of control in the U.S., with the Producer Price Index for “eggs for fresh use” surging 55.6% month-over-month in November and a staggering 80.2% year-over-year, according to official data released Thursday. The Bureau of Labor Statistics highlighted that this single commodity’s price jump accounted for nearly a quarter of November's overall rise in the prices of final-demand goods. While consumers could soon bear the brunt of these producer price increases at their local grocery stores, higher retail prices could translate into stronger profit margins for egg producers. This fact hasn't gone unnoticed by investors. Shares of leading U.S. egg producer Cal-Maine Foods Inc. CALM soared to all-time highs on Thursday, extending a five-day winning streak. Year-to-date, CALM's stock has skyrocketed 87%, far outpacing the broader market, as represented by the SPDR S&P 500 ETF Trust SPY , which is up 28% as of Dec. 12. Meanwhile, smaller competitor Vital Farms Inc. VITAL has seen an even greater rally, surging 142% year to date. Chart: Egg-Linked Stocks Far Outperformed The US Stock Market In 2024 Why You'll Likely Pay More For Eggs At The Grocery Store Soon When producer costs rise, consumers often feel the effects soon after. The PPI, which tracks changes in prices received by producers for their goods, typically serves as a leading indicator for the Consumer Price Index—the measure of what consumers pay. In November, the CPI showed the average price for a dozen Grade A large eggs in the U.S. was $3.64, marking a sharp 70.7% increase from a year earlier. But even that pales in comparison to the January 2023 all-time high of $4.82 per dozen, when the year-over-year increase hit an unprecedented 150%. This massive spike in consumer egg prices followed a period of relentless increases in producer costs. From September 2022 to December 2022, the PPI index for eggs saw monthly gains of 16.6%, 15%, 26%, and 24.5%, with year-over-year increases exceeding 200% by the end of the year. A similar pattern could be unfolding now, foreshadowing even steeper grocery store prices in the coming months. What's Driving Egg Prices Higher? The surge in egg prices can be attributed to a combination of factors, including the devastating effects of avian influenza (bird flu), seasonal demand, and rising production costs. Bird Flu Outbreaks: The U.S. poultry industry has been grappling with ongoing outbreaks of avian influenza, which have led to the culling of millions of laying hens. The reduced flock size has caused a significant supply shortage, pushing prices higher. Seasonal Demand: During the holiday season, egg consumption typically spikes due to increased baking and cooking. Eggs are also viewed as a relatively affordable protein alternative to meat, keeping demand robust even as prices climb. Production Costs: Higher feed and transportation costs are squeezing producers, further inflating wholesale egg prices. These compounding factors have created a perfect storm for the egg market, leading to the recent surge in both producer and consumer prices. The current trajectory of egg prices bears a striking resemblance to late 2022, when producer costs surged for several consecutive months before consumer prices peaked in January 2023. At that time, retail prices shattered records, with some grocery store shelves even running out of stock. If history repeats itself, the worst may be yet to come for U.S. consumers. Read now: Defense Stocks Face Headwinds As Trump’s DOGE Targets Spending Cuts: Goldman Sachs Downgrades General Dynamics Photo: Melnikov Dmitriy/Shutterstock.com © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

British Airways flight attendant 'suspended after callous post about Liam Payne'

Kalonzo urges use of technology for free and fair elections

MINNEAPOLIS (AP) — The Minnesota Timberwolves delayed their game against the San Antonio Spurs by one hour on Sunday night due to an issue with the court at Target Center. The Timberwolves announced the decision about three hours before the originally scheduled tipoff time. The Spurs discovered the problem during their morning shootaround, Timberwolves spokesman Patrick Rees said. The team decided to delay the game so arena staff had enough time to install the replacement court that had to be delivered from elsewhere. The Timberwolves have played at Target Center since 1990. AP NBA: https://apnews.com/hub/NBAHOUSTON--(BUSINESS WIRE)--Dec 3, 2024-- Crescent Energy Company (“Crescent” or the “Company”) (NYSE: CRGY) today announced the commencement of an underwritten public offering of 18,000,000 shares of its Class A common stock, par value $0.0001 per share (“Class A common stock”), pursuant to an effective shelf registration statement on Form S-3 (the “Registration Statement”) filed previously with the U.S. Securities and Exchange Commission (the “SEC”). The Company intends to use the net proceeds it receives from the offering to fund a portion of the cash consideration for its recently announced acquisition of Ridgemar (Eagle Ford) LLC (the “Ridgemar Acquisition”), which is expected to close in the first quarter of 2025, subject to customary closing conditions and regulatory approvals. The Ridgemar Acquisition is not contingent upon the completion of this offering and this offering is not contingent upon the completion of the Ridgemar Acquisition. If the Ridgemar Acquisition is not completed, the proceeds of this offering will be used to reduce the borrowings outstanding under our revolving credit facility or for general corporate purposes. The Company expects to grant the underwriters a 30-day option to purchase up to an additional 2,700,000 shares of Class A common stock at the public offering price, less the underwriting discounts and commissions. Wells Fargo Securities, LLC, KKR Capital Markets LLC, Raymond James & Associates, Inc. and Evercore Group L.L.C. are serving as joint book-running managers for the offering. The offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering. The proposed offering will be made only by means of a prospectus and a prospectus supplement. Copies of the preliminary prospectus supplement and accompanying base prospectus relating to the offering and final prospectus supplement, when available, may be obtained from: Wells Fargo Securities, LLC, 90 South 7th Street, 5th Floor, Minneapolis, MN 55402, at 800-645-3751 (option #5) or email a request to WFScustomerservice@wellsfargo.com , KKR Capital Markets LLC, 30 Hudson Yards, New York, New York 10001 or by telephone at (212) 750-8300, Raymond James & Associates, Inc., 880 Carillon Parkway, St. Petersburg, FL 33716, by telephone at (800) 248-8863 or by email at prospectus@raymondjames.com , or Evercore Group L.L.C., Attention: Equity Capital Markets, 55 East 52nd Street, 35th Floor, New York, New York 10055, by telephone at 888-474-0200 or by email at ecm.prospectus@evercore.com , or by accessing the SEC’s website at www.sec.gov . The offering is being conducted pursuant to the Registration Statement, previously filed with the SEC on March 6, 2024 that became effective upon filing, and corresponding prospectus. A preliminary prospectus supplement thereto has been filed with the SEC. This press release shall not constitute an offer to sell or the solicitation of an offer to buy the shares of Class A common stock or any other securities, nor shall there be any sale of such shares of Class A common stock or any other securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or other jurisdiction. About Crescent Energy Company Crescent Energy Company is a U.S. energy company with a portfolio of assets concentrated in Texas and the Rockies. Cautionary Note Regarding Forward-Looking Statements This communication contains “forward-looking statements” within the meaning of Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder. These forward-looking statements include any statements regarding the proposed offering of Class A common stock and the Ridgemar Acquisition. These forward-looking statements are identified by their use of terms and phrases such as “may,” “expect,” “estimate,” “project,” “plan,” “believe,” “intend,” “achievable,” “anticipate,” “will,” “continue,” “potential,” “should,” “could,” and similar terms and phrases. Although the Company believes that the expectations reflected in these forward-looking statements are reasonable, they do involve certain assumptions, risks and uncertainties. Actual results could differ materially from those anticipated in these forward-looking statements as a result of certain factors, including, but not limited to, those set forth in the Company’s filings with the SEC, including the Registration Statement and the prospectus supplement relating to this offering, its Annual Report on Form 10-K for the fiscal year ended December 31, 2023 and its subsequent Quarterly Reports on Form 10-Q, under the caption “Risk Factors,” as may be updated from time to time in the Company’s periodic filings with the SEC. Any forward-looking statement in this press release speaks only as of the date of this release. The Company undertakes no obligation to publicly update or review any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by any applicable securities laws. View source version on businesswire.com : https://www.businesswire.com/news/home/20241203973333/en/ IR@crescentenergyco.com KEYWORD: TEXAS UNITED STATES NORTH AMERICA INDUSTRY KEYWORD: UTILITIES ENERGY SOURCE: Crescent Energy Copyright Business Wire 2024. PUB: 12/03/2024 04:23 PM/DISC: 12/03/2024 04:23 PM http://www.businesswire.com/news/home/20241203973333/en

Conference stresses urgent need for burn accident awareness Islamabad : National conference stresses urgent need for burn accident awareness and enhanced healthcare facilities calling for public awareness which plays a key role in preventing burn accidents, says a press release. This was stated by Dr. Mukhtar Ahmed, National Health Coordinator, addressing a three-day national conference organised by the Burn Care Centre and Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, in collaboration with the Pakistan Burn Association which concluded here on Saturday. Dr. Mukhtar stressed that the first four to six hours after a burn injury are critical. Timely medical care during this golden window can significantly reduce fatalities. He also highlighted the alarming lack of burn care facilities in hospitals, which has led to higher mortality rates. “There is an urgent need to establish burn wards at the tehsil level and specialized burn centres at the district level to ensure accessible care for burn victims,” he said. HEC Chairman, Professor Mukhtar Ahmed, pointed out the lack of quality research in the medical field and reaffirmed HEC’s commitment to supporting universities through research grants. He called for fostering a culture of advanced research and emphasized organizing awareness sessions on burn prevention in universities across Pakistan. Professor Dr. Tariq Iqbal, Vice-Chancellor and Chairman of the Organizing Committee, underscored the need for legislation to prevent burn incidents. He advocated for the establishment of a National Burn Registry to maintain centralized records of burn patients and called for the implementation of standardized treatment protocols in all hospitals. “Through national prevention programs, we can effectively raise awareness about burn accident prevention,” he added. Highlighting the efforts of the PIMS-affiliated Burn Centre, Dr. Tariq shared that despite limited resources, high-quality treatment is being provided. He noted the dependence on imported supplies like bandages for burn patients but lauded local researchers developing artificial skin through university-led research projects. He also raised concerns about resource constraints that prevent many patients from accessing treatment. Dr. Samia announced the launch of a nationwide awareness campaign on burn accident prevention through the Pakistan Burn Association’s social media platforms. Additionally, the conference resolved to observe National Burn Day annually to sustain public awareness efforts. The next burn conference will be hosted by Mayo Hospital, Lahore.