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There are times when a postseason bowl seems like the first game of next year for the participating teams. That cliche means something a little different for NC State and East Carolina. The Wolfpack and Pirates face each other in the Military Bowl on Saturday in Annapolis, Maryland. Then they'll see each other again in about eight months. NC State opens the 2025 season at home against ECU on Aug. 30. There is certainly plenty of familiarity between these two programs, even though NC State (6-6) is in the ACC and East Carolina (7-5) is in the AAC. The teams — located about 80 miles apart — have met 32 times, most recently in 2022 when the Wolfpack won 21-20. From 1970-87, these teams played each other every year. Since 2004, they haven't gone more than two consecutive seasons without meeting. “Hour and a half down the road and you're playing — whether you play every year or don't play every year — I think it's still a rivalry," East Carolina coach Blake Harrell said. "Our fans still get excited. They still think that's a rivalry. Our players still think that's a rivalry.” NC State leads the series 19-13 and has won three straight — but East Carolina won three in a row before that. “It's weird playing a team that we open with next year,” Wolfpack coach Dave Doeren said. “We don't play them that much. We play them every three years, so it's really a roster turnover. Every time we see them, it's a different ballclub for the most part. But yeah, finishing with who you open with is unique.” NC State and East Carolina met in the Peach Bowl in 1992 — during an eight-year hiatus in their regular-season series. ECU scored three touchdowns in the final 7:26 to win 37-34. “We had that time during COVID, we obviously all had some down time. I remember searching through YouTube, just past games to check out. That game did pop up," Harrell said. "That was a special moment for that team and that program at the time, and this could be a special moment for this team and this program.” NC State is playing in the Military Bowl for the first time. East Carolina was supposed to participate in 2021, but the game was canceled. The Pirates lost to Maryland in the 2010 edition. Harrell took over on an interim basis in the middle of the season when Mike Houston was fired. After leading the Pirates to four straight wins, Harrell had the interim tag removed . Freshman CJ Bailey took over at quarterback for NC State this season after concussion problems ended Grayson McCall's career. Bailey has completed 64.1% of his passes. Only Philip Rivers and Russell Wilson threw for more touchdowns as a freshman for the Wolfpack than Bailey, who has 14 TD tosses. “He's a really good player. Doesn't play like a freshman to me,” Harrell said. "Makes really good throws down the field, has a really good arm, and then if he takes off scrambling or if the quarterback-designed run game, he's a long strider. He can eat up some ground. Nobody ever catches him." Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-footballHere's how Costco, the world's largest warehouse membership club, came to be. Book bargain hunters will be disappointed to learn Costco plans to stop selling books at most of its U.S. stores at the beginning of the year. In January, Costco will remove the store’s popular book section from the majority of its 600-plus stores in the United States. And it will only return during the holiday season, from September to December, and at other intermittent times, the discount store chain told publishers over the summer, according to The New York Times. Costco told the executives the change was made because stocking books on tables is labor-intensive and must be done by hand rather than by forklift like other products, the Times reported. HOW TO SCORE A SELECT COSTCO MEMBERSHIP FOR JUST $20 Book bargain hunters will be disappointed to learn Costco plans to stop selling books at most of its U.S. stores at the beginning of the year. (Justin Sullivan/Getty Images) The decision comes as more consumers are buying books through online outlets like Amazon . Books will remain in around 100 Costco stores across the country all year, however, trade news magazine Publisher’s Weekly reported this week. The decision to keep some books in stores would be a reversal from the store’s earlier plans, the outlet reported. In January, Costco will remove the store’s popular book section from the majority of its 600-plus stores in the United States. (Patrick T. Fallon/AFP via Getty Images) Publishing and Costco executives will also be watching sales trends for Taylor Swift’s official Eras Tour book, which is being sold exclusively at Target starting on Black Friday , Publisher’s Weekly reported. If book sales continue to do well, Costco could bring literary sections back to more stores, according to the magazine, or all of them could become seasonal if sales lag. Shopper looking at Costco books. (Tim Boyle/Getty Images) FOX Business has reached out to Costco for comment. LINK: Get updates on this story and more at foxbusiness.com.jili 63 free 120

REDMOND, Wash., Dec. 06, 2024 (GLOBE NEWSWIRE) -- Pattern Computer®, Inc. (“Pattern” or “the Company”) today announced that it has entered into a multi-target partnership with Phenome Health, a Seattle-based nonprofit research organization led by CEO Lee Hood, MD, PhD. Delivering value through health innovation. Phenome Health employs a data-driven approach to wellness and disease that integrates diverse types of health data. “Pattern is a pioneer in finding novel patterns in complex data that cannot be discovered using other techniques or tools. The speed of AI innovation is accelerating and is rapidly emerging as a strategic imperative. Pattern is optimally positioned to leverage the expertise of our Pattern Discovery EngineTM (PDE) into the next worlds of trustworthy, transparent computing. Since its founding, Pattern has been on a strategic path with a roadmap largely focused on building our PDE and using it to generate world-class, high-value assets. These include and are not limited to seven combination cancer drugs, and new diagnostic advances, against the world’s top five cancers. We seek to partner with firms to bring these therapeutic and diagnostic technologies – such as our ProSpectral TM device, a game-changing medical diagnostic tool and research instrument – into clinical trials,” said Mark Anderson, Chair and CEO. The Partnership will integrate Pattern’s technologies with multi-omics time-course data on individuals with the goal of discovering new drivers of human health and longevity – seeding novel strategies to make these discoveries actionable as part of the standard of care. “By measuring how lifestyle choices impact our short, medium, and long-term health, we will identify genes, pathways, and microbes that can be targeted at a molecular level to improve health, rather than merely treat disease. Our goal in this project is to be instrumental in Phenome Health’s mission to develop the tools and insights that power data-driven personalized health,” Anderson added. Further, the ProSpectral platform will be used to develop surrogate measurements for expensive multi-omics. ProSpectral makes rapid measurements on two drops of saliva that capture rich biochemical information about the individual and their oral microbiome. An early goal will be to determine the extent to which patterns of gene expression, metabolism, and changes in the microbiome can be reconstructed from ProSpectral’s non-invasive, reagent-free assay. Anderson noted, “Success in the integration of ProSpectral with existing multi-omic technologies would reduce the cost of collecting longitudinal molecular data by orders of magnitude – opening precision medicine to regions and economies that are currently priced out of state-of-the-art care. The lightweight, portable nature of our platform ensures that data can be collected anywhere, anytime, without supply chain or economic constraints The rapidity of measurements – seconds instead of hours or days – stands to enable real-time decision support for medical professionals in a way that has never been possible before.” “We are enthusiastic about a partnership with Pattern and the possibilities of identifying non-invasive, rapid, and cost-effective approaches to data-driven personalized health,” added Lee Hood, CEO of Phenome Health. “We envision a world where everyone is empowered by their own data to improve wellness and prevent disease. We see technologies like those developed by Pattern as facilitating this reality.” About Phenome Health Phenome Health was established by internationally acclaimed scientist and entrepreneurial visionary, Lee Hood, to contribute solutions to major challenges causing a crisis in healthcare. The aging population and other factors are driving an explosion of chronic disease that largely contribute to increasing costs at an unsustainable rate in a healthcare system not equipped to solve these problems without a radical paradigm change - namely shifting from a reactive system that focuses on treating disease to a proactive system focused on optimizing health. Economic analysis predicts such a paradigm change would drive trillions of dollars in resources upstream, creating massive opportunity in the health and wellness marketplace. We strive to accelerate this shift through a systematic approach to define health, develop a disease-agnostic discovery framework to understand how and why people transition to disease, and identify new approaches to prevent and reverse disease development. Our ambitious strategy leverages advancements in biotechnologies and computer science to capture and interpret high dimensional health data in order to invent the solutions needed to solve the healthcare crisis. https://phenomehealth.org/ About Pattern Pattern Computer, Inc. uses its Pattern Discovery EngineTM to solve the most important and intractable problems in industry, business and medicine. These proprietary mathematical techniques in advanced AI can find complex patterns in very-high-order data that have eluded detection by much larger systems. As the Company applies its computational platform to the challenging fields of drug discovery and diagnostics in cancer, it is also making major Pattern Discoveries for partners in other sectors, including extended biotech, materials science, aerospace manufacturing quality control, veterinary medicine, air traffic operations, and energy services. See www.patterncomputer.com . CONTACT: Laura Guerrant-Oiye (808) 960-2642 – laura@patterncomputer.com The foregoing contains statements about Pattern Computer’s future that are not statements of historical fact. These statements are “forward looking statements” for purposes of applicable securities laws and are based on current information and/or management’s good faith belief as to future events. The words “believe,” “expect,” “anticipate,” “project,” “should,” “could,” “will,” and similar expressions signify forward-looking statements. Forward-looking statements should not be read as a guarantee of future performance. By their nature, forward-looking statements involve inherent risk and uncertainties, which change over time, and actual performance could differ materially from that anticipated by any forward-looking statements. Pattern Computer undertakes no obligation to update or revise any forward-looking statement. Copyright © 2024 Pattern Computer Inc. All Rights Reserved. Pattern Computer, Inc., Pattern Discovery Engine, PatternBio, TrueXAI, and ProSpectral are trademarks of Pattern Computer Inc. or its subsidiaries. Other trademarks may be trademarks of their respective owners.Local Communities Challenge Michigan Renewable Energy Siting Law

Syrian insurgents reach the capital's suburbs. Worried residents flee and stock up on supplies BEIRUT (AP) — Insurgents’ stunning march across Syria is gaining speed with news that they have reached the suburbs of the capital of Damascus. The government on Saturday was forced to deny rumors that President Bashar Assad had fled the country. The rebels’ moves around Damascus were reported by an opposition war monitor and a rebel commander. They came after the Syrian army withdrew from much of southern part of the country, leaving more areas, including two provincial capitals, under the control of opposition fighters. The advances in the past week were among the largest in recent years by opposition factions. The factions are by a group that has its origins in al-Qaida and is considered a terrorist organization by the U.S. and the United Nations.

Raging Bull Awards: recognising top asset managers over 5 years

The woman who accused then-Fox News host Pete Hegseth of sexual assault in 2017 said that while she did not have a complete recollection of the night in question, she "remembered saying 'no' a lot" and alleged that he prevented her from leaving his hotel room, according to a police report from the Monterey, Calif., police department. The report , which was released to NPR and other outlets after a public records request, provides additional details about the incident involving the woman and Hegseth , who was named last week as President-elect Donald Trump's choice for Secretary of Defense. On Thursday, Karoline Leavitt, Trump-Vance transition spokeswoman said in statement: "This report corroborates what Mr. Hegseth's attorneys have said all along: the incident was fully investigated, and no charges were filed because police found the allegations to be false. Pete Hegseth is a highly-respected Combat Veteran who will honorably serve our country when he is confirmed as the next Secretary of Defense, just like he honorably served our country on the battlefield in uniform." The allegation against Hegseth came into public view just days after President-elect Donald Trump announced him as his nominee for Secretary of Defense, adding to scrutiny of the longtime TV personality's qualifications to lead the Department of Defense. Hegseth, 44, stopped working at Fox News last week after his nomination was announced. His attorney, Timothy Parlatore, said that while Hegseth denies the allegations by his accuser, he settled with her several years ago, to prevent her from filing a lawsuit that could damage his television career. "This police report confirms what I have said all along," Parlatore told NPR via email, "that the incident was fully investigated and police found the allegations to be false, which is why no charges were filed." Monterey County District Attorney Jeannine M. Pacioni said in a statement to NPR that her office declined to pursue the case in early 2018, after determining that "No charges were supported by proof beyond a reasonable doubt." What do the two sides say? The woman is identified only as Jane Doe in the police document. She told an investigator that late one night, while in Hegseth's room at a hotel that was hosting a Republican women's conference, he took her cellphone and "blocked the door with his body," according to the report. She also said they then had a sexual encounter, and in the ensuing days as other events triggered memories, she "went to the hospital because she believed she was sexually assaulted by [Hegseth]," an officer wrote in the report. The incidents described in the police report occurred over several hours, from Saturday evening, Oct. 7, into the early hours of Sunday, Oct. 8. When police contacted Hegseth later that month, his version of events differed from Doe's; as he told an investigator that he and Doe had had sex -- but that it was consensual. Both Hegseth and Doe say they had been drinking alcohol that night, as they and others moved from a banquet and speech to an afterparty and then late-night drinks at the bar at the Hyatt Regency Monterey Hotel and Spa. The resort was hosting a conference and party for the California Federation of Republican Women. Doe, a staffer for the organization, was staying at the hotel with her husband. Why is the report coming out now? City Attorney Christine Davi says her office determined that it could release the redacted police report because Hegseth had been given a copy of the same document in March of 2021 -- rendering it no longer exempt from release under the state's public records laws. Other records, including a separate police report from another agency; a Kaiser Permanente report; an audio recording; surveillance footage; a photograph; and a memo from the Monterey County District Attorney's Office remain confidential, Davi says. What about accounts from witnesses and video? Witnesses describe roughly the same general arc of movement, as Hegseth, Doe and others moved from the hotel's conference center and ballroom to an after party spanning several suites. Later, Doe and Hegseth were part of a smaller group that went to the hotel's bar, called Knuckles Sports Bar. Witnesses and hotel records stated that Hegseth and Doe had a loud argument along the pool deck around 1:30 a.m. -- prompting an employee to ask them to be quiet. Hegseth responded by cursing at the employee and saying "he had freedom of speech," according to the police report. Doe then intervened, telling the employee "that they were Republicans and apologized" for Hegseth's behavior. The employee said Hegseth and Doe left soon afterward. They ended up in Building 5, room 528 -- Hegseth's room. What did Jane Doe tell police? In text messages Doe shared with police, she mentioned meeting Hegseth at the conference, including a message saying, "our ladies are freaking drooling over him." Some of Doe's texts were in conversations with her husband. Some of them indicated that she was not impressed with Hegseth, noting, "He wears a ring on his pointer finger. It creeps me out." Later in the evening, Doe told investigators, she saw Hegseth "acting inappropriately," rubbing women's legs, and "giving off a 'creeper' vibe," according to the report. In her statements to police, Doe described how memories of that night came back to her. Of the visit to Knuckles bar, she said, "that's when things got fuzzy." She told police that she recalled arguing with Hegseth near the pool, saying it was about how he was treating women at the conference. Doe remembered Hegseth telling her "that he was a nice guy," according to the report. "[Doe] stated the next memory she had was when she was in an unknown room," according to the police report. "[Doe] did not know where she was and how she got to the room. [Hegseth] was in the room with her." The report states that the woman said Hegseth asked who she was texting with and took her phone. Doe told police that she then tried to leave the room, but Hegseth blocked the door. "[Doe] remembered saying "no" a lot. [Doe] stated she did not remember much else. [Doe's] next memory was when she was on a bed or a couch and [Hegseth] was over her. [Hegseth's] dog tags were hovering over her face." What did Hegseth tell police? Hegseth told police that he delivered the keynote speech at the conference. Later, he said, he went upstairs to the after-party where he drank beer. He said that he and others then went to the hotel bar. Police say that the hotel's surveillance footage shows him, Doe and another woman walking to the bar, in a video time-stamped close to midnight. Hegseth said that no one at the bar was "blacked out drunk," and that while he was "buzzed," he wasn't intoxicated, according to the report. Hegseth told police he didn't remember having an argument at the pool. He said he was confused that Doe went back to his hotel room with him, because they had not talked as much as he did with others. Hegseth maintained that any physical interaction between them was consensual. Afterward, he said, Doe told him she would tell her husband that she had fallen asleep on a couch in someone else's room. Before Doe left his room, Hegseth said, he told her he would stay quiet about what had happened — but he added that she "showed early signs of regret." He did not specify what those signs were. How did the police get involved? Police were alerted when a Kaiser Permanente nurse called them on Oct. 12, 2017, reporting that a woman had come in requesting a sexual assault exam. The patient wanted to remain anonymous -- known as Jane Doe -- and she initially did not tell police Hegseth's name either, according to the report. The nurse said the patient was referred to an emergency room for an examination. The 22-page police report includes input from at least three officers, beginning with the officer who handled the initial call to an investigator who followed up and spoke with Doe, other women who were with her that night; hotel employees; and Hegseth himself. The report concludes with a recommendation to forward the case to the Monterey County District Attorney's Office for review. It lists the potential criminal offense as "Rape: victim unconscious of the nature of the act" -- citing California penal code section 261(a) (4) . Under state law, rape is classified as a felony punishable by three to eight years in prison. Copyright 2024 NPR

Wholesale Chain Costco To Stop Selling Books | Here's Why

Liard First Nation Celebrates Opening Elders Housing Complex in Watson Lake: Strengthening Community ConnectionsAkron routs Division III-SUNY-Brockport 101-48

Iowa moves on without injured quarterback Brendan Sullivan when the Hawkeyes visit Maryland for a Big Ten Conference contest on Saturday afternoon. Former starter Cade McNamara is not ready to return from a concussion, so Iowa (6-4, 4-3) turns to former walk-on and fourth-stringer Jackson Stratton to lead the offense in College Park, Md. "Confident that he'll do a great job," Iowa coach Kirk Ferentz said of Stratton on his weekly radio show. "He stepped in, did a really nice job in our last ballgame. And he's got a good ability to throw the football, and he's learning every day. ... We'll go with him and see what we can do." Iowa had been on an upswing with Sullivan, who had sparked the Hawkeyes to convincing wins over Northwestern and Wisconsin before suffering an ankle injury in a 20-17 loss at UCLA on Nov. 8. Stratton came on in relief against the Bruins and completed 3 of 6 passes for 28 yards. Another storyline for Saturday is that Ferentz will be opposing his son, Brian Ferentz, an assistant at Maryland. Brian Ferentz was Iowa's offensive coordinator from 2017-23. "We've all got business to take care of on Saturday," Kirk Ferentz said. "I think his experience has been good and everything I know about it. As a parent, I'm glad he's with good people." Maryland (4-6, 1-6) needs a win to keep its hopes alive for a fourth straight bowl appearance under Mike Locksley. The Terrapins have dropped five of their last six games, all by at least 14 points, including a 31-17 loss at home to Rutgers last weekend. "It's been a challenging last few weeks to say the least," Locksley said. The challenge this week will be to stop Iowa running back Kaleb Johnson, who leads the Big Ten in rushing yards (1,328) and touchdowns (20), averaging 7.1 yards per carry. "With running backs, it's not always about speed. It's about power, vision and the ability to make something out of nothing," Locksley said. "This guy is a load and runs behind his pads." Maryland answers with quarterback Billy Edwards Jr., who leads the Big Ten in passing yards per game (285.5) and completions (268). His top target is Tai Felton, who leads the conference in catches (86) and receiving yards (1,040). --Field Level Media

Tomley shot 7 for 12 (6 for 7 from 3-point range) and 8 of 8 from the free-throw line for the Wildcats (4-4). Blaise Threatt added 21 points and seven rebounds. Boubacar Coulibaly led the Waves (2-6) with 17 points, 11 rebounds and two blocks. Stefan Todorovic added 13 points and Zion Bethea scored 12. Weber State took the lead with 9:18 remaining in the first half and did not relinquish it. The score was 33-23 at halftime, with Tomley racking up 11 points. T The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

There are times when a postseason bowl seems like the first game of next year for the participating teams. That cliche means something a little different for NC State and East Carolina. The Wolfpack and Pirates face each other in the Military Bowl on Saturday in Annapolis, Maryland. Then they'll see each other again in about eight months. NC State opens the 2025 season at home against ECU on Aug. 30. There is certainly plenty of familiarity between these two programs, even though NC State (6-6) is in the ACC and East Carolina (7-5) is in the AAC. The teams — located about 80 miles apart — have met 32 times, most recently in 2022 when the Wolfpack won 21-20. From 1970-87, these teams played each other every year. Since 2004, they haven't gone more than two consecutive seasons without meeting. “Hour and a half down the road and you're playing — whether you play every year or don't play every year — I think it's still a rivalry," East Carolina coach Blake Harrell said. "Our fans still get excited. They still think that's a rivalry. Our players still think that's a rivalry.” NC State leads the series 19-13 and has won three straight — but East Carolina won three in a row before that. “It's weird playing a team that we open with next year,” Wolfpack coach Dave Doeren said. “We don't play them that much. We play them every three years, so it's really a roster turnover. Every time we see them, it's a different ballclub for the most part. But yeah, finishing with who you open with is unique.” NC State and East Carolina met in the Peach Bowl in 1992 — during an eight-year hiatus in their regular-season series. ECU scored three touchdowns in the final 7:26 to win 37-34. “We had that time during COVID, we obviously all had some down time. I remember searching through YouTube, just past games to check out. That game did pop up," Harrell said. "That was a special moment for that team and that program at the time, and this could be a special moment for this team and this program.” NC State is playing in the Military Bowl for the first time. East Carolina was supposed to participate in 2021, but the game was canceled. The Pirates lost to Maryland in the 2010 edition. Harrell took over on an interim basis in the middle of the season when Mike Houston was fired. After leading the Pirates to four straight wins, Harrell had the interim tag removed . Freshman CJ Bailey took over at quarterback for NC State this season after concussion problems ended Grayson McCall's career. Bailey has completed 64.1% of his passes. Only Philip Rivers and Russell Wilson threw for more touchdowns as a freshman for the Wolfpack than Bailey, who has 14 TD tosses. “He's a really good player. Doesn't play like a freshman to me,” Harrell said. "Makes really good throws down the field, has a really good arm, and then if he takes off scrambling or if the quarterback-designed run game, he's a long strider. He can eat up some ground. Nobody ever catches him." Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-footballHere's how Costco, the world's largest warehouse membership club, came to be. Book bargain hunters will be disappointed to learn Costco plans to stop selling books at most of its U.S. stores at the beginning of the year. In January, Costco will remove the store’s popular book section from the majority of its 600-plus stores in the United States. And it will only return during the holiday season, from September to December, and at other intermittent times, the discount store chain told publishers over the summer, according to The New York Times. Costco told the executives the change was made because stocking books on tables is labor-intensive and must be done by hand rather than by forklift like other products, the Times reported. HOW TO SCORE A SELECT COSTCO MEMBERSHIP FOR JUST $20 Book bargain hunters will be disappointed to learn Costco plans to stop selling books at most of its U.S. stores at the beginning of the year. (Justin Sullivan/Getty Images) The decision comes as more consumers are buying books through online outlets like Amazon . Books will remain in around 100 Costco stores across the country all year, however, trade news magazine Publisher’s Weekly reported this week. The decision to keep some books in stores would be a reversal from the store’s earlier plans, the outlet reported. In January, Costco will remove the store’s popular book section from the majority of its 600-plus stores in the United States. (Patrick T. Fallon/AFP via Getty Images) Publishing and Costco executives will also be watching sales trends for Taylor Swift’s official Eras Tour book, which is being sold exclusively at Target starting on Black Friday , Publisher’s Weekly reported. If book sales continue to do well, Costco could bring literary sections back to more stores, according to the magazine, or all of them could become seasonal if sales lag. Shopper looking at Costco books. (Tim Boyle/Getty Images) FOX Business has reached out to Costco for comment. LINK: Get updates on this story and more at foxbusiness.com.jili 63 free 120

REDMOND, Wash., Dec. 06, 2024 (GLOBE NEWSWIRE) -- Pattern Computer®, Inc. (“Pattern” or “the Company”) today announced that it has entered into a multi-target partnership with Phenome Health, a Seattle-based nonprofit research organization led by CEO Lee Hood, MD, PhD. Delivering value through health innovation. Phenome Health employs a data-driven approach to wellness and disease that integrates diverse types of health data. “Pattern is a pioneer in finding novel patterns in complex data that cannot be discovered using other techniques or tools. The speed of AI innovation is accelerating and is rapidly emerging as a strategic imperative. Pattern is optimally positioned to leverage the expertise of our Pattern Discovery EngineTM (PDE) into the next worlds of trustworthy, transparent computing. Since its founding, Pattern has been on a strategic path with a roadmap largely focused on building our PDE and using it to generate world-class, high-value assets. These include and are not limited to seven combination cancer drugs, and new diagnostic advances, against the world’s top five cancers. We seek to partner with firms to bring these therapeutic and diagnostic technologies – such as our ProSpectral TM device, a game-changing medical diagnostic tool and research instrument – into clinical trials,” said Mark Anderson, Chair and CEO. The Partnership will integrate Pattern’s technologies with multi-omics time-course data on individuals with the goal of discovering new drivers of human health and longevity – seeding novel strategies to make these discoveries actionable as part of the standard of care. “By measuring how lifestyle choices impact our short, medium, and long-term health, we will identify genes, pathways, and microbes that can be targeted at a molecular level to improve health, rather than merely treat disease. Our goal in this project is to be instrumental in Phenome Health’s mission to develop the tools and insights that power data-driven personalized health,” Anderson added. Further, the ProSpectral platform will be used to develop surrogate measurements for expensive multi-omics. ProSpectral makes rapid measurements on two drops of saliva that capture rich biochemical information about the individual and their oral microbiome. An early goal will be to determine the extent to which patterns of gene expression, metabolism, and changes in the microbiome can be reconstructed from ProSpectral’s non-invasive, reagent-free assay. Anderson noted, “Success in the integration of ProSpectral with existing multi-omic technologies would reduce the cost of collecting longitudinal molecular data by orders of magnitude – opening precision medicine to regions and economies that are currently priced out of state-of-the-art care. The lightweight, portable nature of our platform ensures that data can be collected anywhere, anytime, without supply chain or economic constraints The rapidity of measurements – seconds instead of hours or days – stands to enable real-time decision support for medical professionals in a way that has never been possible before.” “We are enthusiastic about a partnership with Pattern and the possibilities of identifying non-invasive, rapid, and cost-effective approaches to data-driven personalized health,” added Lee Hood, CEO of Phenome Health. “We envision a world where everyone is empowered by their own data to improve wellness and prevent disease. We see technologies like those developed by Pattern as facilitating this reality.” About Phenome Health Phenome Health was established by internationally acclaimed scientist and entrepreneurial visionary, Lee Hood, to contribute solutions to major challenges causing a crisis in healthcare. The aging population and other factors are driving an explosion of chronic disease that largely contribute to increasing costs at an unsustainable rate in a healthcare system not equipped to solve these problems without a radical paradigm change - namely shifting from a reactive system that focuses on treating disease to a proactive system focused on optimizing health. Economic analysis predicts such a paradigm change would drive trillions of dollars in resources upstream, creating massive opportunity in the health and wellness marketplace. We strive to accelerate this shift through a systematic approach to define health, develop a disease-agnostic discovery framework to understand how and why people transition to disease, and identify new approaches to prevent and reverse disease development. Our ambitious strategy leverages advancements in biotechnologies and computer science to capture and interpret high dimensional health data in order to invent the solutions needed to solve the healthcare crisis. https://phenomehealth.org/ About Pattern Pattern Computer, Inc. uses its Pattern Discovery EngineTM to solve the most important and intractable problems in industry, business and medicine. These proprietary mathematical techniques in advanced AI can find complex patterns in very-high-order data that have eluded detection by much larger systems. As the Company applies its computational platform to the challenging fields of drug discovery and diagnostics in cancer, it is also making major Pattern Discoveries for partners in other sectors, including extended biotech, materials science, aerospace manufacturing quality control, veterinary medicine, air traffic operations, and energy services. See www.patterncomputer.com . CONTACT: Laura Guerrant-Oiye (808) 960-2642 – laura@patterncomputer.com The foregoing contains statements about Pattern Computer’s future that are not statements of historical fact. These statements are “forward looking statements” for purposes of applicable securities laws and are based on current information and/or management’s good faith belief as to future events. The words “believe,” “expect,” “anticipate,” “project,” “should,” “could,” “will,” and similar expressions signify forward-looking statements. Forward-looking statements should not be read as a guarantee of future performance. By their nature, forward-looking statements involve inherent risk and uncertainties, which change over time, and actual performance could differ materially from that anticipated by any forward-looking statements. Pattern Computer undertakes no obligation to update or revise any forward-looking statement. Copyright © 2024 Pattern Computer Inc. All Rights Reserved. Pattern Computer, Inc., Pattern Discovery Engine, PatternBio, TrueXAI, and ProSpectral are trademarks of Pattern Computer Inc. or its subsidiaries. Other trademarks may be trademarks of their respective owners.Local Communities Challenge Michigan Renewable Energy Siting Law

Syrian insurgents reach the capital's suburbs. Worried residents flee and stock up on supplies BEIRUT (AP) — Insurgents’ stunning march across Syria is gaining speed with news that they have reached the suburbs of the capital of Damascus. The government on Saturday was forced to deny rumors that President Bashar Assad had fled the country. The rebels’ moves around Damascus were reported by an opposition war monitor and a rebel commander. They came after the Syrian army withdrew from much of southern part of the country, leaving more areas, including two provincial capitals, under the control of opposition fighters. The advances in the past week were among the largest in recent years by opposition factions. The factions are by a group that has its origins in al-Qaida and is considered a terrorist organization by the U.S. and the United Nations.

Raging Bull Awards: recognising top asset managers over 5 years

The woman who accused then-Fox News host Pete Hegseth of sexual assault in 2017 said that while she did not have a complete recollection of the night in question, she "remembered saying 'no' a lot" and alleged that he prevented her from leaving his hotel room, according to a police report from the Monterey, Calif., police department. The report , which was released to NPR and other outlets after a public records request, provides additional details about the incident involving the woman and Hegseth , who was named last week as President-elect Donald Trump's choice for Secretary of Defense. On Thursday, Karoline Leavitt, Trump-Vance transition spokeswoman said in statement: "This report corroborates what Mr. Hegseth's attorneys have said all along: the incident was fully investigated, and no charges were filed because police found the allegations to be false. Pete Hegseth is a highly-respected Combat Veteran who will honorably serve our country when he is confirmed as the next Secretary of Defense, just like he honorably served our country on the battlefield in uniform." The allegation against Hegseth came into public view just days after President-elect Donald Trump announced him as his nominee for Secretary of Defense, adding to scrutiny of the longtime TV personality's qualifications to lead the Department of Defense. Hegseth, 44, stopped working at Fox News last week after his nomination was announced. His attorney, Timothy Parlatore, said that while Hegseth denies the allegations by his accuser, he settled with her several years ago, to prevent her from filing a lawsuit that could damage his television career. "This police report confirms what I have said all along," Parlatore told NPR via email, "that the incident was fully investigated and police found the allegations to be false, which is why no charges were filed." Monterey County District Attorney Jeannine M. Pacioni said in a statement to NPR that her office declined to pursue the case in early 2018, after determining that "No charges were supported by proof beyond a reasonable doubt." What do the two sides say? The woman is identified only as Jane Doe in the police document. She told an investigator that late one night, while in Hegseth's room at a hotel that was hosting a Republican women's conference, he took her cellphone and "blocked the door with his body," according to the report. She also said they then had a sexual encounter, and in the ensuing days as other events triggered memories, she "went to the hospital because she believed she was sexually assaulted by [Hegseth]," an officer wrote in the report. The incidents described in the police report occurred over several hours, from Saturday evening, Oct. 7, into the early hours of Sunday, Oct. 8. When police contacted Hegseth later that month, his version of events differed from Doe's; as he told an investigator that he and Doe had had sex -- but that it was consensual. Both Hegseth and Doe say they had been drinking alcohol that night, as they and others moved from a banquet and speech to an afterparty and then late-night drinks at the bar at the Hyatt Regency Monterey Hotel and Spa. The resort was hosting a conference and party for the California Federation of Republican Women. Doe, a staffer for the organization, was staying at the hotel with her husband. Why is the report coming out now? City Attorney Christine Davi says her office determined that it could release the redacted police report because Hegseth had been given a copy of the same document in March of 2021 -- rendering it no longer exempt from release under the state's public records laws. Other records, including a separate police report from another agency; a Kaiser Permanente report; an audio recording; surveillance footage; a photograph; and a memo from the Monterey County District Attorney's Office remain confidential, Davi says. What about accounts from witnesses and video? Witnesses describe roughly the same general arc of movement, as Hegseth, Doe and others moved from the hotel's conference center and ballroom to an after party spanning several suites. Later, Doe and Hegseth were part of a smaller group that went to the hotel's bar, called Knuckles Sports Bar. Witnesses and hotel records stated that Hegseth and Doe had a loud argument along the pool deck around 1:30 a.m. -- prompting an employee to ask them to be quiet. Hegseth responded by cursing at the employee and saying "he had freedom of speech," according to the police report. Doe then intervened, telling the employee "that they were Republicans and apologized" for Hegseth's behavior. The employee said Hegseth and Doe left soon afterward. They ended up in Building 5, room 528 -- Hegseth's room. What did Jane Doe tell police? In text messages Doe shared with police, she mentioned meeting Hegseth at the conference, including a message saying, "our ladies are freaking drooling over him." Some of Doe's texts were in conversations with her husband. Some of them indicated that she was not impressed with Hegseth, noting, "He wears a ring on his pointer finger. It creeps me out." Later in the evening, Doe told investigators, she saw Hegseth "acting inappropriately," rubbing women's legs, and "giving off a 'creeper' vibe," according to the report. In her statements to police, Doe described how memories of that night came back to her. Of the visit to Knuckles bar, she said, "that's when things got fuzzy." She told police that she recalled arguing with Hegseth near the pool, saying it was about how he was treating women at the conference. Doe remembered Hegseth telling her "that he was a nice guy," according to the report. "[Doe] stated the next memory she had was when she was in an unknown room," according to the police report. "[Doe] did not know where she was and how she got to the room. [Hegseth] was in the room with her." The report states that the woman said Hegseth asked who she was texting with and took her phone. Doe told police that she then tried to leave the room, but Hegseth blocked the door. "[Doe] remembered saying "no" a lot. [Doe] stated she did not remember much else. [Doe's] next memory was when she was on a bed or a couch and [Hegseth] was over her. [Hegseth's] dog tags were hovering over her face." What did Hegseth tell police? Hegseth told police that he delivered the keynote speech at the conference. Later, he said, he went upstairs to the after-party where he drank beer. He said that he and others then went to the hotel bar. Police say that the hotel's surveillance footage shows him, Doe and another woman walking to the bar, in a video time-stamped close to midnight. Hegseth said that no one at the bar was "blacked out drunk," and that while he was "buzzed," he wasn't intoxicated, according to the report. Hegseth told police he didn't remember having an argument at the pool. He said he was confused that Doe went back to his hotel room with him, because they had not talked as much as he did with others. Hegseth maintained that any physical interaction between them was consensual. Afterward, he said, Doe told him she would tell her husband that she had fallen asleep on a couch in someone else's room. Before Doe left his room, Hegseth said, he told her he would stay quiet about what had happened — but he added that she "showed early signs of regret." He did not specify what those signs were. How did the police get involved? Police were alerted when a Kaiser Permanente nurse called them on Oct. 12, 2017, reporting that a woman had come in requesting a sexual assault exam. The patient wanted to remain anonymous -- known as Jane Doe -- and she initially did not tell police Hegseth's name either, according to the report. The nurse said the patient was referred to an emergency room for an examination. The 22-page police report includes input from at least three officers, beginning with the officer who handled the initial call to an investigator who followed up and spoke with Doe, other women who were with her that night; hotel employees; and Hegseth himself. The report concludes with a recommendation to forward the case to the Monterey County District Attorney's Office for review. It lists the potential criminal offense as "Rape: victim unconscious of the nature of the act" -- citing California penal code section 261(a) (4) . Under state law, rape is classified as a felony punishable by three to eight years in prison. Copyright 2024 NPR

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Iowa moves on without injured quarterback Brendan Sullivan when the Hawkeyes visit Maryland for a Big Ten Conference contest on Saturday afternoon. Former starter Cade McNamara is not ready to return from a concussion, so Iowa (6-4, 4-3) turns to former walk-on and fourth-stringer Jackson Stratton to lead the offense in College Park, Md. "Confident that he'll do a great job," Iowa coach Kirk Ferentz said of Stratton on his weekly radio show. "He stepped in, did a really nice job in our last ballgame. And he's got a good ability to throw the football, and he's learning every day. ... We'll go with him and see what we can do." Iowa had been on an upswing with Sullivan, who had sparked the Hawkeyes to convincing wins over Northwestern and Wisconsin before suffering an ankle injury in a 20-17 loss at UCLA on Nov. 8. Stratton came on in relief against the Bruins and completed 3 of 6 passes for 28 yards. Another storyline for Saturday is that Ferentz will be opposing his son, Brian Ferentz, an assistant at Maryland. Brian Ferentz was Iowa's offensive coordinator from 2017-23. "We've all got business to take care of on Saturday," Kirk Ferentz said. "I think his experience has been good and everything I know about it. As a parent, I'm glad he's with good people." Maryland (4-6, 1-6) needs a win to keep its hopes alive for a fourth straight bowl appearance under Mike Locksley. The Terrapins have dropped five of their last six games, all by at least 14 points, including a 31-17 loss at home to Rutgers last weekend. "It's been a challenging last few weeks to say the least," Locksley said. The challenge this week will be to stop Iowa running back Kaleb Johnson, who leads the Big Ten in rushing yards (1,328) and touchdowns (20), averaging 7.1 yards per carry. "With running backs, it's not always about speed. It's about power, vision and the ability to make something out of nothing," Locksley said. "This guy is a load and runs behind his pads." Maryland answers with quarterback Billy Edwards Jr., who leads the Big Ten in passing yards per game (285.5) and completions (268). His top target is Tai Felton, who leads the conference in catches (86) and receiving yards (1,040). --Field Level Media

Tomley shot 7 for 12 (6 for 7 from 3-point range) and 8 of 8 from the free-throw line for the Wildcats (4-4). Blaise Threatt added 21 points and seven rebounds. Boubacar Coulibaly led the Waves (2-6) with 17 points, 11 rebounds and two blocks. Stefan Todorovic added 13 points and Zion Bethea scored 12. Weber State took the lead with 9:18 remaining in the first half and did not relinquish it. The score was 33-23 at halftime, with Tomley racking up 11 points. T The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

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