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Sir Keir Starmer said Mr Carter, who died aged 100, will be remembered for the Camp David Accords between Israel and Egypt. Sir Keir Starmer has led a host of tributes to former US president Jimmy Carter, saying he “redefined the post-presidency with a remarkable commitment to social justice and human rights at home and abroad”. The Prime Minister said Mr Carter, who died aged 100, will be remembered for the Camp David Accords between Israel and Egypt, as well as his “decades of selfless public service”. He added that it was the Democrat’s “lifelong dedication to peace” that led to him receiving the Nobel Peace prize in 2002. Sir Keir was joined in paying tribute to the 39th president by other leaders including the King, current President Joe Biden, Lib Dem leader Sir Ed Davey and former PM Tony Blair. The King remembered former US president Jimmy Carter’s 1977 visit to the UK with “great fondness” and praised his “dedication and humility”. In a message to Mr Biden and the American people, Charles said: “It was with great sadness that I learned of the death of President Carter. “He was a committed public servant, and devoted his life to promoting peace and human rights. “His dedication and humility served as an inspiration to many, and I remember with great fondness his visit to the United Kingdom in 1977. “My thoughts and prayers are with President Carter’s family and the American people at this time.” Mr Biden said that Mr Carter was an “extraordinary leader, statesman and humanitarian”. He said his fellow Democrat was a “dear friend”, as he announced that he will order a state funeral to be held for him in Washington DC. “Today, America and the world lost an extraordinary leader, statesman and humanitarian,” he said. “Over six decades, we had the honour of calling Jimmy Carter a dear friend. But, what’s extraordinary about Jimmy Carter though is that millions of people throughout America and the world who never met him thought of him as a dear friend as well. “With his compassion and moral clarity, he worked to eradicate disease, forge peace, advance civil rights and human rights, promote free and fair elections, house the homeless, and always advocate for the least among us. He saved, lifted and changed the lives of people all across the globe. “He was a man of great character and courage, hope and optimism.” Lib Dem leader Sir Ed Davey said Mr Carter “will be remembered for generations”. “Jimmy Carter was an inspiration,” Mr Davey wrote on X. “He led a truly remarkable life dedicated to public service with a genuine care for people. “My thoughts are with his family, friends and all those who loved him. He will be remembered for generations.” Mr Blair said: “Jimmy Carter’s life was a testament to public service; from his time in office, and the Camp David Accords, to his remarkable commitment to the cause of people and peace round the world over the past 40 years,” he said. “I always had the greatest respect for him, his spirit and his dedication. He fundamentally cared and consistently toiled to help those in need.”
CLEVELAND (AP) — Alyssa Nakken, the first woman to coach in a Major League Baseball game, is leaving the San Francisco Giants to join the Cleveland Guardians. Nakken made history in 2022 when she took over as first-base coach following an ejection. A former college softball star at Sacramento State, Nakken joined the Giants in 2014 and was promoted to a spot on manager Gabe Kapler's staff in 2020, becoming the majors' first full-time female coach. Nakken has been hired as an assistant director within player development for the Guardians, who won the AL Central last season under first-year manager Stephen Vogt — the AL Manager of the Year. With Cleveland, the 34-year-old Nakken will work with former Giants coaches Craig Albernaz and Kai Correa. Her exact duties are still being determined. "We thank Alyssa Nakken for her incredible contributions to the San Francisco Giants and for trailblazing a path for women in sports,” the Giants said in a statement on Friday. "Her leadership, dedication, and passion for the game have inspired countless individuals, and her impact has been truly transformative for the Giants organization and the baseball community. “As she embarks on this exciting new chapter in her career, we have no doubt that she’ll continue to inspire and achieve great things. We wish her and her family nothing but the best.” Nakken is the second on-field female coach hired by the Guardians. In 2023, the club brought in Amanda Kamekona as their hitting development coach for their year-round training academy in Goodyear, Arizona. Last season, she was an assistant hitting coach at Double-A Akron. Kamekona was twice a third-team All-American at UCLA after transferring from Cal State Fullerton. AP MLB: https://apnews.com/hub/mlbArmy marks Asom Diwas with studentsLiverpool power seven points clear, Man Utd crash at Wolves
South Korea lifts president's martial law decree after lawmakers reject military rule
Shares of Rockfire Resources plc ( LON:ROCK – Get Free Report ) were down 8.9% during trading on Saturday . The company traded as low as GBX 0.16 ($0.00) and last traded at GBX 0.16 ($0.00). Approximately 40,381,969 shares were traded during mid-day trading, an increase of 91% from the average daily volume of 21,155,254 shares. The stock had previously closed at GBX 0.18 ($0.00). Rockfire Resources Stock Down 8.9 % The business’s 50-day moving average price is GBX 0.13 and its 200 day moving average price is GBX 0.15. The company has a market capitalization of £5.07 million, a P/E ratio of -2.20 and a beta of 0.38. About Rockfire Resources ( Get Free Report ) Rockfire Resources plc, together with its subsidiaries, engages in the mineral exploration in Australia. The company explores for gold, silver, copper, zinc, lead, and molybdenum deposits. It holds five exploration permits for minerals in Queensland; and an exploration and exploitation license in Greece. See Also Receive News & Ratings for Rockfire Resources Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Rockfire Resources and related companies with MarketBeat.com's FREE daily email newsletter .Sunday's showdown between the Philadelphia 76ers and visiting Los Angeles Clippers is not going to materialize in the way Paul George had hoped. After five seasons with the Clippers, George signed a four-year, $212 million deal with the Sixers in the offseason. However, the team has won only three times in its first 15 games with stars Joel Embiid, Tyrese Maxey and George all missing significant time due to injuries. Embiid continues to nurse a knee injury and will miss this matchup, while George (hyperextended knee) will not be available to face his former team. Meanwhile, the Clippers have been up-and-down this season while playing the entire campaign without two-way standout Kawhi Leonard (knee). Los Angeles opened the season 2-1 before losing three in a row. The team then won four straight, then lost three consecutive games and now has won four straight entering Sunday's opener of a four-game road trip. The Clippers announced over the weekend that Leonard would miss the entire trip, which puts more pressure on former Sixers guard James Harden, who is averaging 20.4 points, 7.6 rebounds and a team-high 8.8 assists. Norman Powell is the Clippers' leading scorer at 23.3 points per game. He will miss his third consecutive game with a hamstring issue. The Clippers won twice at home without Powell, including Friday's 104-88 triumph over the Sacramento Kings. Harden had 22 points to lead the way in that contest, while Ivica Zubac notched 10 points and 15 rebounds. "All games are meaningful for us," Clippers coach Tyronn Lue said after the win in NBA Cup play. "Playing for the Cup and having a chance to go to Vegas to play for the big money is always intriguing as well. But we got to play the same way every night, whether it's the Cup, whatever we are doing, being short-handed." After committing 22 turnovers in the victory over the Orlando Magic on Wednesday, the Clippers committed just 12 turnovers against the Kings. "We've just got to take care of the basketball," Lue said. That will be particularly important Sunday against a Philadelphia squad that forced 19 turnovers in Friday's 113-98 victory over the Brooklyn Nets. On the offensive end, rookie Jared McCain and All-Star guard Tyrese Maxey combined for 56 points as the Sixers snapped a five-game slide. "I ain't gonna lie, it felt good to win," Maxey said after shooting 11-of-17 for 26 points. "I'm not going to sit here and talk about making shots. We played so hard, offensively and defensively, (and) played together. Guys stuck together." McCain was caught on camera in the fourth quarter saying, "I'm Rookie of the Year." The guard finished with 30 points -- his seventh straight game with at least 20 points. "It's one of my goals for the season, obviously," McCain said, "but it was just that competitiveness coming out of me. I respect every other rookie in this league, but obviously I'm a believer in myself and so, yeah, some words definitely came out at that point." The teams met Nov. 6 in Los Angeles, where the Clippers posted a comfortable 110-98 victory behind 26 points from Powell. This article first appeared on Field Level Media and was syndicated with permission.
By JILL COLVIN and STEPHEN GROVES WASHINGTON (AP) — After several weeks working mostly behind closed doors, Vice President-elect JD Vance returned to Capitol Hill this week in a new, more visible role: Helping Donald Trump try to get his most contentious Cabinet picks to confirmation in the Senate, where Vance has served for the last two years. Vance arrived at the Capitol on Wednesday with former Rep. Matt Gaetz and spent the morning sitting in on meetings between Trump’s choice for attorney general and key Republicans, including members of the Senate Judiciary Committee. The effort was for naught: Gaetz announced a day later that he was withdrawing his name amid scrutiny over sex trafficking allegations and the reality that he was unlikely to be confirmed. Thursday morning Vance was back, this time accompanying Pete Hegseth, the “Fox & Friends Weekend” host whom Trump has tapped to be the next secretary of defense. Hegseth also has faced allegations of sexual assault that he denies. Vance is expected to accompany other nominees for meetings in coming weeks as he tries to leverage the two years he has spent in the Senate to help push through Trump’s picks. Vice President-elect JD Vance, still a Republican senator from Ohio, walks from a private meeting with President-elect Donald Trump’s nominee to be attorney general, former Rep. Matt Gaetz, R-Fla., at the Capitol in Washington, Wednesday, Nov. 20, 2024. (AP Photo/J. Scott Applewhite) President-elect Donald Trump’s nominee to be attorney general, former Rep. Matt Gaetz, R-Fla., center, and Vice President-elect JD Vance, left, walk out of a meeting with Republican Senate Judiciary Committee members, at the Capitol in Washington, Wednesday, Nov. 20, 2024. (AP Photo/Ben Curtis) FILE – Sen. JD Vance, R-Ohio, departs the chamber at the Capitol in Washington, March 15, 2023. (AP Photo/J. Scott Applewhite, File) FILE – Sen. JD Vance, R-Ohio, center speaks during a Senate Banking Committee hearing on Capitol Hill in Washington, March 7, 2023. (AP Photo/Andrew Harnik, File) FILE – Sen. JD Vance, R-Ohio, right, speaks with Sen. Sherrod Brown, D-Ohio, before testifying at a hearing, March 9, 2023, in Washington. (AP Photo/Kevin Wolf, File) FILE – Sen. JD Vance, R-Ohio, arrives for a classified briefing on China, at the Capitol in Washington, Feb. 15, 2023. (AP Photo/J. Scott Applewhite, File) FILE – Sen. JD Vance, R-Ohio, arrives for a vote on Capitol Hill, Sept. 12, 2023 in Washington. (AP Photo/Mark Schiefelbein, File) FILE – Sen. JD Vance R-Ohio speaks during a news conference on Capitol Hill in Washington, Feb. 6, 2024. (AP Photo/Jose Luis Magana, File) Vice President-elect JD Vance, still a Republican senator from Ohio, walks from a private meeting with President-elect Donald Trump’s nominee to be attorney general, former Rep. Matt Gaetz, R-Fla., at the Capitol in Washington, Wednesday, Nov. 20, 2024. (AP Photo/J. Scott Applewhite) The role of introducing nominees around Capitol Hill is an unusual one for a vice president-elect. Usually the job goes to a former senator who has close relationships on the Hill, or a more junior aide. But this time the role fits Vance, said Marc Short, who served as Trump’s first director of legislative affairs as well as chief of staff to Trump’s first vice president, Mike Pence, who spent more than a decade in Congress and led the former president’s transition ahead of his first term. ”JD probably has a lot of current allies in the Senate and so it makes sense to have him utilized in that capacity,” Short said. Unlike the first Trump transition, which played out before cameras at Trump Tower in New York and at the president-elect’s golf club in Bedminster, New Jersey, this one has largely happened behind closed doors in Palm Beach, Florida. There, a small group of officials and aides meet daily at Trump’s Mar-a-Lago resort to run through possible contenders and interview job candidates. The group includes Elon Musk, the billionaire who has spent so much time at the club that Trump has joked he can’t get rid of him. Vance has been a constant presence, even as he’s kept a lower profile. The Ohio senator has spent much of the last two weeks in Palm Beach, according to people familiar with his plans, playing an active role in the transition, on which he serves as honorary chair. Vance has been staying at a cottage on the property of the gilded club, where rooms are adorned with cherubs, oriental rugs and intricate golden inlays. It’s a world away from the famously hardscrabble upbringing that Vance documented in the memoir that made him famous, “Hillbilly Elegy.” His young children have also joined him at Mar-a-Lago, at times. Vance was photographed in shorts and a polo shirt playing with his kids on the seawall of the property with a large palm frond, a U.S. Secret Service robotic security dog in the distance. On the rare days when he is not in Palm Beach, Vance has been joining the sessions remotely via Zoom. Though he has taken a break from TV interviews after months of constant appearances, Vance has been active in the meetings, which began immediately after the election and include interviews and as well as presentations on candidates’ pluses and minuses. Among those interviewed: Contenders to replace FBI Director Christopher Wray , as Vance wrote in a since-deleted social media post. Defending himself from criticism that he’d missed a Senate vote in which one of President Joe Biden’s judicial nominees was confirmed, Vance wrote that he was meeting at the time “with President Trump to interview multiple positions for our government, including for FBI Director.” “I tend to think it’s more important to get an FBI director who will dismantle the deep state than it is for Republicans to lose a vote 49-46 rather than 49-45,” Vance added on X. “But that’s just me.” While Vance did not come in to the transition with a list of people he wanted to see in specific roles, he and his friend, Trump’s eldest son, Donald Trump Jr., who is also a member of the transition team, were eager to see former Democratic Rep. Tulsi Gabbard and Robert F. Kennedy Jr. find roles in the administration. Trump ended up selecting Gabbard as the next director of national intelligence , a powerful position that sits atop the nation’s spy agencies and acts as the president’s top intelligence adviser. And he chose Kennedy to lead the Department of Health and Human Services , a massive agency that oversees everything from drug and food safety to Medicare and Medicaid. Vance was also a big booster of Tom Homan, the former acting director of Immigration and Customs Enforcement, who will serve as Trump’s “border czar.” In another sign of Vance’s influence, James Braid, a top aide to the senator, is expected to serve as Trump’s legislative affairs director. Allies say it’s too early to discuss what portfolio Vance might take on in the White House. While he gravitates to issues like trade, immigration and tech policy, Vance sees his role as doing whatever Trump needs. Vance was spotted days after the election giving his son’s Boy Scout troop a tour of the Capitol and was there the day of leadership elections. He returned in earnest this week, first with Gaetz — arguably Trump’s most divisive pick — and then Hegseth, who has was been accused of sexually assaulting a woman in 2017, according to an investigative report made public this week. Hegseth told police at the time that the encounter had been consensual and denied any wrongdoing. Vance hosted Hegseth in his Senate office as GOP senators, including those who sit on the Senate Armed Services Committee, filtered in to meet with the nominee for defense secretary. While a president’s nominees usually visit individual senators’ offices, meeting them on their own turf, the freshman senator — who is accompanied everywhere by a large Secret Service detail that makes moving around more unwieldy — instead brought Gaetz to a room in the Capitol on Wednesday and Hegseth to his office on Thursday. Senators came to them. Vance made it to votes Wednesday and Thursday, but missed others on Thursday afternoon. Vance is expected to continue to leverage his relationships in the Senate after Trump takes office. But many Republicans there have longer relationships with Trump himself. Sen. Kevin Cramer, a North Dakota Republican, said that Trump was often the first person to call him back when he was trying to reach high-level White House officials during Trump’s first term. “He has the most active Rolodex of just about anybody I’ve ever known,” Cramer said, adding that Vance would make a good addition. “They’ll divide names up by who has the most persuasion here,” Cramer said, but added, “Whoever his liaison is will not work as hard at it as he will.” Cramer was complimentary of the Ohio senator, saying he was “pleasant” and ” interesting” to be around. ′′He doesn’t have the long relationships,” he said. “But we all like people that have done what we’ve done. I mean, that’s sort of a natural kinship, just probably not as personally tied.” Under the Constitution, Vance will also have a role presiding over the Senate and breaking tie votes. But he’s not likely to be needed for that as often as was Kamala Harris, who broke a record number of ties for Democrats as vice president, since Republicans will have a bigger cushion in the chamber next year. Colvin reported from New York. Associated Press writer Mary Clare Jalonick contributed to this report.Dazostinag sodium is under clinical development by and currently in Phase I for Non-Small Cell Lung Cancer. According to GlobalData, Phase I drugs for Non-Small Cell Lung Cancer have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Dazostinag sodium overview Dazostinag sodium (TAK-676) is under development for the treatment of advanced or metastatic solid tumors including non-small cell lung cancer, triple-negative breast cancer (TNBC), oropharyngeal cancer, colorectal cancer and head and neck cancer squamous cell carcinoma. The drug candidate is cyclic purine dinucleotide and acts by targeting stimulator of interferon genes (STING/TMEM173). It is a new molecular entity. It is administered via intravenous route. Takeda Pharmaceutical overview (Takeda) is a global pharmaceutical company primarily engaged in the research, development, production, and commercialization of biopharmaceutical products. It provides treatment for inflammatory bowel disease, acid-related diseases, motility disorders and liver diseases; hemophilia and hereditary bleeding disorders; primary immunodeficiency and multifocal motor neuropathy; major depressive disorder and attention-deficit hyperactivity disorder; and its cancer treatment encompasses multiple myeloma, mantle cell lymphoma, non-small cell lung cancer and chronic myeloid leukemia. While the company markets its pharmaceutical products directly, it also collaborates with marketing alliance partners in worldwide. Takeda operates in various countries worldwide, including Japan, the US, Europe, Latin America, Africa, the Middle East, and the Asia Pacific region. Takeda is headquartered in Tokyo, Japan. For a complete picture of Dazostinag sodium’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .
Russia pioneers next-gen nuclear energyIn 2024, I watched, tested and reviewed more TVs than I can count. I've gawked at some of the best OLEDs I've ever seen, I've had my eyes blasted by bright, colorful Mini-LEDs and I've glimpsed the future of ultra-affordable 4K TVs. In the spirit of ringing in the new year (and in the spirit of end-of-year lists), I'm picking my favorite TVs across multiple price points. All of them are on sale, too, ahead of CES 2025 . 1. TCL Q6: my favorite QLED under $500 I've recommended this TV to three separate friends and family members this year with the exact same pitch each time: If you're just looking for an affordable TV with easy-to-use smart features, this is the one. The TCL Q6 is a dependable QLED with an accurate out-of-the-box picture and Google TV baked right in. Right now, the 65-inch TCL Q6 is just $399 at Best Buy . In 4K, its gaming support is limited to 60Hz, but you'll get ultra-low latency with an input lag of below 10ms, and the Q6 is bright enough to look good in most living rooms. You can read more about it in our full TCL Q6 review , but we thought it checked most of the boxes for a budget-friendly, set-it-and-forget-it set. Other sizes on sale: 55-inch TCL Q6: was $449 now $269 @ Best Buy 75-inch TCL Q6: was $749 now $529 @ Best Buy 2. Hisense U7N: my favorite Mini-LED TV under $1,000 If you're a casual or competitive gamer on a budget, or just someone who's looking for a good amount of HDR horsepower for movies and shows, the Hisense U7N is just the ticket. It's the brand's mid-range Mini-LED for 2024, and I really appreciate what it has to offer for the price. Right now, a 65-inch Hisense U7N is just $697 at Amazon. In our Hisense U7N review , we marveled at its tremendous HDR performance, as it sports over 1,300 nits of highlight brightness during HDR movies and games while its Mini-LED backlighting keeps contrast in check. It delivers nearly all of the gaming features one would expect from a higher-end TV, too, including support for 4K gaming at up to 144Hz and VRR. Other sizes on sale: 55-inch Hisense U7N: was $798 now $497 @ Amazon 75-inch Hisense U7N: was $1,499 now $899 @ Best Buy 3. LG B4: my favorite OLED under $1,500 The LG B4 is one of my favorite TVs of the year. It's not as bright as higher-end OLEDs, nor is it as thoroughly loaded with features. But it is an OLED TV, which means it's a real showstopper thanks to the built-in benefits of this impressive display technology (namely, perfect black levels and ultra-wide viewing angles). The 65-inch LG B4 is just $1,196 at Amazon , but most of the other sizes are on sale, too. You can read all about it in our LG B4 review , but this set offers excellent color volume (with fantastic accuracy in Filmmaker mode) along with some crucial gaming enhancements. It supports 4K gaming at 120Hz across all four of its HDMI 2.1 inputs. Other sizes on sale: 48-inch LG B4: was $799 now $699 @ Best Buy 55-inch LG B4: was $1,099 now $996 @ Amazon 4. LG C4: my favorite OLED under $2,000 The LG C4 lives up to its pedigree with incredible performance and a more agreeable price tag than you'd expect. It's one of the best TVs of the year in this price range, and right now, you can land a 65-inch LG C4 for $1,496 at Amazon . The C4 is the TV to get if you're looking for an OLED that's brighter than the B4 but not as pricey as a flagship model. In our LG C4 review, we noted the TV's impressive HDR brightness: over 1,000 nits for impressive specular highlights. The C4 also comes with pretty much every gaming feature you could ask for. It supports 4K gaming up to 144Hz, delivers VRR, FreeSync, and G-Sync compatibility, and LG's Game Optimizer mode is among the best in the biz. Other sizes on sale: 48-inch LG C4: was $1,599 now $1,196 @ Amazon 55-inch LG C4: was $1,296 now $1,196 @ Amazon 77-inch LG C4: was $3,699 now $2,196 @ Amazon 5. Sony Bravia 9: my favorite flagship Mini-LED TV It's been a highly competitive year for Mini-LED TVs, but if you were to drop a small sack of money on my lap and tell me to pick out my favorite of 2024, it would undoubtedly go to the Sony Bravia 9. It's a pricey proposition, as the 65-inch Sony Bravia 9 is on sale for $2,498 at Amazon . That's more than you'd spend on most of its competitors, so why do I love it so much? The Bravia 9 may not be the best Mini-LED for most people, but to my eyes, it's got some of the most impressive backlight control and picture processing I've ever seen. It also gets brighter than everything else on this list. For our Bravia 9 review , we measured HDR highlights in the 2,500- to 3,000-nit range. The Bravia 9 is limited to just a pair of HDMI 2.1 inputs with the remaining ports being HDMI 2.0. If you're a serious gamer or home theater enthusiast, this could be less than ideal. If you're committed to owning one of the best Mini-LED TVs on the market, splash out on Sony's top-of-the-line Bravia.

Sir Keir Starmer said Mr Carter, who died aged 100, will be remembered for the Camp David Accords between Israel and Egypt. Sir Keir Starmer has led a host of tributes to former US president Jimmy Carter, saying he “redefined the post-presidency with a remarkable commitment to social justice and human rights at home and abroad”. The Prime Minister said Mr Carter, who died aged 100, will be remembered for the Camp David Accords between Israel and Egypt, as well as his “decades of selfless public service”. He added that it was the Democrat’s “lifelong dedication to peace” that led to him receiving the Nobel Peace prize in 2002. Sir Keir was joined in paying tribute to the 39th president by other leaders including the King, current President Joe Biden, Lib Dem leader Sir Ed Davey and former PM Tony Blair. The King remembered former US president Jimmy Carter’s 1977 visit to the UK with “great fondness” and praised his “dedication and humility”. In a message to Mr Biden and the American people, Charles said: “It was with great sadness that I learned of the death of President Carter. “He was a committed public servant, and devoted his life to promoting peace and human rights. “His dedication and humility served as an inspiration to many, and I remember with great fondness his visit to the United Kingdom in 1977. “My thoughts and prayers are with President Carter’s family and the American people at this time.” Mr Biden said that Mr Carter was an “extraordinary leader, statesman and humanitarian”. He said his fellow Democrat was a “dear friend”, as he announced that he will order a state funeral to be held for him in Washington DC. “Today, America and the world lost an extraordinary leader, statesman and humanitarian,” he said. “Over six decades, we had the honour of calling Jimmy Carter a dear friend. But, what’s extraordinary about Jimmy Carter though is that millions of people throughout America and the world who never met him thought of him as a dear friend as well. “With his compassion and moral clarity, he worked to eradicate disease, forge peace, advance civil rights and human rights, promote free and fair elections, house the homeless, and always advocate for the least among us. He saved, lifted and changed the lives of people all across the globe. “He was a man of great character and courage, hope and optimism.” Lib Dem leader Sir Ed Davey said Mr Carter “will be remembered for generations”. “Jimmy Carter was an inspiration,” Mr Davey wrote on X. “He led a truly remarkable life dedicated to public service with a genuine care for people. “My thoughts are with his family, friends and all those who loved him. He will be remembered for generations.” Mr Blair said: “Jimmy Carter’s life was a testament to public service; from his time in office, and the Camp David Accords, to his remarkable commitment to the cause of people and peace round the world over the past 40 years,” he said. “I always had the greatest respect for him, his spirit and his dedication. He fundamentally cared and consistently toiled to help those in need.”
CLEVELAND (AP) — Alyssa Nakken, the first woman to coach in a Major League Baseball game, is leaving the San Francisco Giants to join the Cleveland Guardians. Nakken made history in 2022 when she took over as first-base coach following an ejection. A former college softball star at Sacramento State, Nakken joined the Giants in 2014 and was promoted to a spot on manager Gabe Kapler's staff in 2020, becoming the majors' first full-time female coach. Nakken has been hired as an assistant director within player development for the Guardians, who won the AL Central last season under first-year manager Stephen Vogt — the AL Manager of the Year. With Cleveland, the 34-year-old Nakken will work with former Giants coaches Craig Albernaz and Kai Correa. Her exact duties are still being determined. "We thank Alyssa Nakken for her incredible contributions to the San Francisco Giants and for trailblazing a path for women in sports,” the Giants said in a statement on Friday. "Her leadership, dedication, and passion for the game have inspired countless individuals, and her impact has been truly transformative for the Giants organization and the baseball community. “As she embarks on this exciting new chapter in her career, we have no doubt that she’ll continue to inspire and achieve great things. We wish her and her family nothing but the best.” Nakken is the second on-field female coach hired by the Guardians. In 2023, the club brought in Amanda Kamekona as their hitting development coach for their year-round training academy in Goodyear, Arizona. Last season, she was an assistant hitting coach at Double-A Akron. Kamekona was twice a third-team All-American at UCLA after transferring from Cal State Fullerton. AP MLB: https://apnews.com/hub/mlbArmy marks Asom Diwas with studentsLiverpool power seven points clear, Man Utd crash at Wolves
South Korea lifts president's martial law decree after lawmakers reject military rule
Shares of Rockfire Resources plc ( LON:ROCK – Get Free Report ) were down 8.9% during trading on Saturday . The company traded as low as GBX 0.16 ($0.00) and last traded at GBX 0.16 ($0.00). Approximately 40,381,969 shares were traded during mid-day trading, an increase of 91% from the average daily volume of 21,155,254 shares. The stock had previously closed at GBX 0.18 ($0.00). Rockfire Resources Stock Down 8.9 % The business’s 50-day moving average price is GBX 0.13 and its 200 day moving average price is GBX 0.15. The company has a market capitalization of £5.07 million, a P/E ratio of -2.20 and a beta of 0.38. About Rockfire Resources ( Get Free Report ) Rockfire Resources plc, together with its subsidiaries, engages in the mineral exploration in Australia. The company explores for gold, silver, copper, zinc, lead, and molybdenum deposits. It holds five exploration permits for minerals in Queensland; and an exploration and exploitation license in Greece. See Also Receive News & Ratings for Rockfire Resources Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Rockfire Resources and related companies with MarketBeat.com's FREE daily email newsletter .Sunday's showdown between the Philadelphia 76ers and visiting Los Angeles Clippers is not going to materialize in the way Paul George had hoped. After five seasons with the Clippers, George signed a four-year, $212 million deal with the Sixers in the offseason. However, the team has won only three times in its first 15 games with stars Joel Embiid, Tyrese Maxey and George all missing significant time due to injuries. Embiid continues to nurse a knee injury and will miss this matchup, while George (hyperextended knee) will not be available to face his former team. Meanwhile, the Clippers have been up-and-down this season while playing the entire campaign without two-way standout Kawhi Leonard (knee). Los Angeles opened the season 2-1 before losing three in a row. The team then won four straight, then lost three consecutive games and now has won four straight entering Sunday's opener of a four-game road trip. The Clippers announced over the weekend that Leonard would miss the entire trip, which puts more pressure on former Sixers guard James Harden, who is averaging 20.4 points, 7.6 rebounds and a team-high 8.8 assists. Norman Powell is the Clippers' leading scorer at 23.3 points per game. He will miss his third consecutive game with a hamstring issue. The Clippers won twice at home without Powell, including Friday's 104-88 triumph over the Sacramento Kings. Harden had 22 points to lead the way in that contest, while Ivica Zubac notched 10 points and 15 rebounds. "All games are meaningful for us," Clippers coach Tyronn Lue said after the win in NBA Cup play. "Playing for the Cup and having a chance to go to Vegas to play for the big money is always intriguing as well. But we got to play the same way every night, whether it's the Cup, whatever we are doing, being short-handed." After committing 22 turnovers in the victory over the Orlando Magic on Wednesday, the Clippers committed just 12 turnovers against the Kings. "We've just got to take care of the basketball," Lue said. That will be particularly important Sunday against a Philadelphia squad that forced 19 turnovers in Friday's 113-98 victory over the Brooklyn Nets. On the offensive end, rookie Jared McCain and All-Star guard Tyrese Maxey combined for 56 points as the Sixers snapped a five-game slide. "I ain't gonna lie, it felt good to win," Maxey said after shooting 11-of-17 for 26 points. "I'm not going to sit here and talk about making shots. We played so hard, offensively and defensively, (and) played together. Guys stuck together." McCain was caught on camera in the fourth quarter saying, "I'm Rookie of the Year." The guard finished with 30 points -- his seventh straight game with at least 20 points. "It's one of my goals for the season, obviously," McCain said, "but it was just that competitiveness coming out of me. I respect every other rookie in this league, but obviously I'm a believer in myself and so, yeah, some words definitely came out at that point." The teams met Nov. 6 in Los Angeles, where the Clippers posted a comfortable 110-98 victory behind 26 points from Powell. This article first appeared on Field Level Media and was syndicated with permission.
By JILL COLVIN and STEPHEN GROVES WASHINGTON (AP) — After several weeks working mostly behind closed doors, Vice President-elect JD Vance returned to Capitol Hill this week in a new, more visible role: Helping Donald Trump try to get his most contentious Cabinet picks to confirmation in the Senate, where Vance has served for the last two years. Vance arrived at the Capitol on Wednesday with former Rep. Matt Gaetz and spent the morning sitting in on meetings between Trump’s choice for attorney general and key Republicans, including members of the Senate Judiciary Committee. The effort was for naught: Gaetz announced a day later that he was withdrawing his name amid scrutiny over sex trafficking allegations and the reality that he was unlikely to be confirmed. Thursday morning Vance was back, this time accompanying Pete Hegseth, the “Fox & Friends Weekend” host whom Trump has tapped to be the next secretary of defense. Hegseth also has faced allegations of sexual assault that he denies. Vance is expected to accompany other nominees for meetings in coming weeks as he tries to leverage the two years he has spent in the Senate to help push through Trump’s picks. Vice President-elect JD Vance, still a Republican senator from Ohio, walks from a private meeting with President-elect Donald Trump’s nominee to be attorney general, former Rep. Matt Gaetz, R-Fla., at the Capitol in Washington, Wednesday, Nov. 20, 2024. (AP Photo/J. Scott Applewhite) President-elect Donald Trump’s nominee to be attorney general, former Rep. Matt Gaetz, R-Fla., center, and Vice President-elect JD Vance, left, walk out of a meeting with Republican Senate Judiciary Committee members, at the Capitol in Washington, Wednesday, Nov. 20, 2024. (AP Photo/Ben Curtis) FILE – Sen. JD Vance, R-Ohio, departs the chamber at the Capitol in Washington, March 15, 2023. (AP Photo/J. Scott Applewhite, File) FILE – Sen. JD Vance, R-Ohio, center speaks during a Senate Banking Committee hearing on Capitol Hill in Washington, March 7, 2023. (AP Photo/Andrew Harnik, File) FILE – Sen. JD Vance, R-Ohio, right, speaks with Sen. Sherrod Brown, D-Ohio, before testifying at a hearing, March 9, 2023, in Washington. (AP Photo/Kevin Wolf, File) FILE – Sen. JD Vance, R-Ohio, arrives for a classified briefing on China, at the Capitol in Washington, Feb. 15, 2023. (AP Photo/J. Scott Applewhite, File) FILE – Sen. JD Vance, R-Ohio, arrives for a vote on Capitol Hill, Sept. 12, 2023 in Washington. (AP Photo/Mark Schiefelbein, File) FILE – Sen. JD Vance R-Ohio speaks during a news conference on Capitol Hill in Washington, Feb. 6, 2024. (AP Photo/Jose Luis Magana, File) Vice President-elect JD Vance, still a Republican senator from Ohio, walks from a private meeting with President-elect Donald Trump’s nominee to be attorney general, former Rep. Matt Gaetz, R-Fla., at the Capitol in Washington, Wednesday, Nov. 20, 2024. (AP Photo/J. Scott Applewhite) The role of introducing nominees around Capitol Hill is an unusual one for a vice president-elect. Usually the job goes to a former senator who has close relationships on the Hill, or a more junior aide. But this time the role fits Vance, said Marc Short, who served as Trump’s first director of legislative affairs as well as chief of staff to Trump’s first vice president, Mike Pence, who spent more than a decade in Congress and led the former president’s transition ahead of his first term. ”JD probably has a lot of current allies in the Senate and so it makes sense to have him utilized in that capacity,” Short said. Unlike the first Trump transition, which played out before cameras at Trump Tower in New York and at the president-elect’s golf club in Bedminster, New Jersey, this one has largely happened behind closed doors in Palm Beach, Florida. There, a small group of officials and aides meet daily at Trump’s Mar-a-Lago resort to run through possible contenders and interview job candidates. The group includes Elon Musk, the billionaire who has spent so much time at the club that Trump has joked he can’t get rid of him. Vance has been a constant presence, even as he’s kept a lower profile. The Ohio senator has spent much of the last two weeks in Palm Beach, according to people familiar with his plans, playing an active role in the transition, on which he serves as honorary chair. Vance has been staying at a cottage on the property of the gilded club, where rooms are adorned with cherubs, oriental rugs and intricate golden inlays. It’s a world away from the famously hardscrabble upbringing that Vance documented in the memoir that made him famous, “Hillbilly Elegy.” His young children have also joined him at Mar-a-Lago, at times. Vance was photographed in shorts and a polo shirt playing with his kids on the seawall of the property with a large palm frond, a U.S. Secret Service robotic security dog in the distance. On the rare days when he is not in Palm Beach, Vance has been joining the sessions remotely via Zoom. Though he has taken a break from TV interviews after months of constant appearances, Vance has been active in the meetings, which began immediately after the election and include interviews and as well as presentations on candidates’ pluses and minuses. Among those interviewed: Contenders to replace FBI Director Christopher Wray , as Vance wrote in a since-deleted social media post. Defending himself from criticism that he’d missed a Senate vote in which one of President Joe Biden’s judicial nominees was confirmed, Vance wrote that he was meeting at the time “with President Trump to interview multiple positions for our government, including for FBI Director.” “I tend to think it’s more important to get an FBI director who will dismantle the deep state than it is for Republicans to lose a vote 49-46 rather than 49-45,” Vance added on X. “But that’s just me.” While Vance did not come in to the transition with a list of people he wanted to see in specific roles, he and his friend, Trump’s eldest son, Donald Trump Jr., who is also a member of the transition team, were eager to see former Democratic Rep. Tulsi Gabbard and Robert F. Kennedy Jr. find roles in the administration. Trump ended up selecting Gabbard as the next director of national intelligence , a powerful position that sits atop the nation’s spy agencies and acts as the president’s top intelligence adviser. And he chose Kennedy to lead the Department of Health and Human Services , a massive agency that oversees everything from drug and food safety to Medicare and Medicaid. Vance was also a big booster of Tom Homan, the former acting director of Immigration and Customs Enforcement, who will serve as Trump’s “border czar.” In another sign of Vance’s influence, James Braid, a top aide to the senator, is expected to serve as Trump’s legislative affairs director. Allies say it’s too early to discuss what portfolio Vance might take on in the White House. While he gravitates to issues like trade, immigration and tech policy, Vance sees his role as doing whatever Trump needs. Vance was spotted days after the election giving his son’s Boy Scout troop a tour of the Capitol and was there the day of leadership elections. He returned in earnest this week, first with Gaetz — arguably Trump’s most divisive pick — and then Hegseth, who has was been accused of sexually assaulting a woman in 2017, according to an investigative report made public this week. Hegseth told police at the time that the encounter had been consensual and denied any wrongdoing. Vance hosted Hegseth in his Senate office as GOP senators, including those who sit on the Senate Armed Services Committee, filtered in to meet with the nominee for defense secretary. While a president’s nominees usually visit individual senators’ offices, meeting them on their own turf, the freshman senator — who is accompanied everywhere by a large Secret Service detail that makes moving around more unwieldy — instead brought Gaetz to a room in the Capitol on Wednesday and Hegseth to his office on Thursday. Senators came to them. Vance made it to votes Wednesday and Thursday, but missed others on Thursday afternoon. Vance is expected to continue to leverage his relationships in the Senate after Trump takes office. But many Republicans there have longer relationships with Trump himself. Sen. Kevin Cramer, a North Dakota Republican, said that Trump was often the first person to call him back when he was trying to reach high-level White House officials during Trump’s first term. “He has the most active Rolodex of just about anybody I’ve ever known,” Cramer said, adding that Vance would make a good addition. “They’ll divide names up by who has the most persuasion here,” Cramer said, but added, “Whoever his liaison is will not work as hard at it as he will.” Cramer was complimentary of the Ohio senator, saying he was “pleasant” and ” interesting” to be around. ′′He doesn’t have the long relationships,” he said. “But we all like people that have done what we’ve done. I mean, that’s sort of a natural kinship, just probably not as personally tied.” Under the Constitution, Vance will also have a role presiding over the Senate and breaking tie votes. But he’s not likely to be needed for that as often as was Kamala Harris, who broke a record number of ties for Democrats as vice president, since Republicans will have a bigger cushion in the chamber next year. Colvin reported from New York. Associated Press writer Mary Clare Jalonick contributed to this report.Dazostinag sodium is under clinical development by and currently in Phase I for Non-Small Cell Lung Cancer. According to GlobalData, Phase I drugs for Non-Small Cell Lung Cancer have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Dazostinag sodium overview Dazostinag sodium (TAK-676) is under development for the treatment of advanced or metastatic solid tumors including non-small cell lung cancer, triple-negative breast cancer (TNBC), oropharyngeal cancer, colorectal cancer and head and neck cancer squamous cell carcinoma. The drug candidate is cyclic purine dinucleotide and acts by targeting stimulator of interferon genes (STING/TMEM173). It is a new molecular entity. It is administered via intravenous route. Takeda Pharmaceutical overview (Takeda) is a global pharmaceutical company primarily engaged in the research, development, production, and commercialization of biopharmaceutical products. It provides treatment for inflammatory bowel disease, acid-related diseases, motility disorders and liver diseases; hemophilia and hereditary bleeding disorders; primary immunodeficiency and multifocal motor neuropathy; major depressive disorder and attention-deficit hyperactivity disorder; and its cancer treatment encompasses multiple myeloma, mantle cell lymphoma, non-small cell lung cancer and chronic myeloid leukemia. While the company markets its pharmaceutical products directly, it also collaborates with marketing alliance partners in worldwide. Takeda operates in various countries worldwide, including Japan, the US, Europe, Latin America, Africa, the Middle East, and the Asia Pacific region. Takeda is headquartered in Tokyo, Japan. For a complete picture of Dazostinag sodium’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .
Russia pioneers next-gen nuclear energyIn 2024, I watched, tested and reviewed more TVs than I can count. I've gawked at some of the best OLEDs I've ever seen, I've had my eyes blasted by bright, colorful Mini-LEDs and I've glimpsed the future of ultra-affordable 4K TVs. In the spirit of ringing in the new year (and in the spirit of end-of-year lists), I'm picking my favorite TVs across multiple price points. All of them are on sale, too, ahead of CES 2025 . 1. TCL Q6: my favorite QLED under $500 I've recommended this TV to three separate friends and family members this year with the exact same pitch each time: If you're just looking for an affordable TV with easy-to-use smart features, this is the one. The TCL Q6 is a dependable QLED with an accurate out-of-the-box picture and Google TV baked right in. Right now, the 65-inch TCL Q6 is just $399 at Best Buy . In 4K, its gaming support is limited to 60Hz, but you'll get ultra-low latency with an input lag of below 10ms, and the Q6 is bright enough to look good in most living rooms. You can read more about it in our full TCL Q6 review , but we thought it checked most of the boxes for a budget-friendly, set-it-and-forget-it set. Other sizes on sale: 55-inch TCL Q6: was $449 now $269 @ Best Buy 75-inch TCL Q6: was $749 now $529 @ Best Buy 2. Hisense U7N: my favorite Mini-LED TV under $1,000 If you're a casual or competitive gamer on a budget, or just someone who's looking for a good amount of HDR horsepower for movies and shows, the Hisense U7N is just the ticket. It's the brand's mid-range Mini-LED for 2024, and I really appreciate what it has to offer for the price. Right now, a 65-inch Hisense U7N is just $697 at Amazon. In our Hisense U7N review , we marveled at its tremendous HDR performance, as it sports over 1,300 nits of highlight brightness during HDR movies and games while its Mini-LED backlighting keeps contrast in check. It delivers nearly all of the gaming features one would expect from a higher-end TV, too, including support for 4K gaming at up to 144Hz and VRR. Other sizes on sale: 55-inch Hisense U7N: was $798 now $497 @ Amazon 75-inch Hisense U7N: was $1,499 now $899 @ Best Buy 3. LG B4: my favorite OLED under $1,500 The LG B4 is one of my favorite TVs of the year. It's not as bright as higher-end OLEDs, nor is it as thoroughly loaded with features. But it is an OLED TV, which means it's a real showstopper thanks to the built-in benefits of this impressive display technology (namely, perfect black levels and ultra-wide viewing angles). The 65-inch LG B4 is just $1,196 at Amazon , but most of the other sizes are on sale, too. You can read all about it in our LG B4 review , but this set offers excellent color volume (with fantastic accuracy in Filmmaker mode) along with some crucial gaming enhancements. It supports 4K gaming at 120Hz across all four of its HDMI 2.1 inputs. Other sizes on sale: 48-inch LG B4: was $799 now $699 @ Best Buy 55-inch LG B4: was $1,099 now $996 @ Amazon 4. LG C4: my favorite OLED under $2,000 The LG C4 lives up to its pedigree with incredible performance and a more agreeable price tag than you'd expect. It's one of the best TVs of the year in this price range, and right now, you can land a 65-inch LG C4 for $1,496 at Amazon . The C4 is the TV to get if you're looking for an OLED that's brighter than the B4 but not as pricey as a flagship model. In our LG C4 review, we noted the TV's impressive HDR brightness: over 1,000 nits for impressive specular highlights. The C4 also comes with pretty much every gaming feature you could ask for. It supports 4K gaming up to 144Hz, delivers VRR, FreeSync, and G-Sync compatibility, and LG's Game Optimizer mode is among the best in the biz. Other sizes on sale: 48-inch LG C4: was $1,599 now $1,196 @ Amazon 55-inch LG C4: was $1,296 now $1,196 @ Amazon 77-inch LG C4: was $3,699 now $2,196 @ Amazon 5. Sony Bravia 9: my favorite flagship Mini-LED TV It's been a highly competitive year for Mini-LED TVs, but if you were to drop a small sack of money on my lap and tell me to pick out my favorite of 2024, it would undoubtedly go to the Sony Bravia 9. It's a pricey proposition, as the 65-inch Sony Bravia 9 is on sale for $2,498 at Amazon . That's more than you'd spend on most of its competitors, so why do I love it so much? The Bravia 9 may not be the best Mini-LED for most people, but to my eyes, it's got some of the most impressive backlight control and picture processing I've ever seen. It also gets brighter than everything else on this list. For our Bravia 9 review , we measured HDR highlights in the 2,500- to 3,000-nit range. The Bravia 9 is limited to just a pair of HDMI 2.1 inputs with the remaining ports being HDMI 2.0. If you're a serious gamer or home theater enthusiast, this could be less than ideal. If you're committed to owning one of the best Mini-LED TVs on the market, splash out on Sony's top-of-the-line Bravia.