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ATLANTA — President Jimmy Carter’s work making the world a better place will continue because of his faith, a dogged determination to leave a mark on the planet and a curious late-night dream. He left the White House in bitter disappointment and frustration in early 1981 at not having a second term because of the ascendance of Ronald Reagan. The ambitious Carter was not content to build a presidential library and rest on the laurels of a Mideast peace treaty, a nuclear arms deal with the Soviet Union, expanding national parks and reemphasizing human rights in American foreign policy. There was much left undone, in his estimation, but how to go about it now that he was out of the bully pulpit? He and his wife Rosalynn decided to leverage the prestige of his being a former president into opening doors and continuing work addressing poverty, illnesses and democracy around the world. Carter said in a 2009 interview with The Atlanta Journal-Constitution that they realized there could be advantages in working without the shackles of congressional approvals, presidential protocols or inter-party politics. He and Rosalynn would later talk about whether he was able to accomplish more in the world through the Carter Center than he would have as a second-term president. “I think yes,” Carter told the AJC. He reemphasized his satisfaction with his decision during an August 2015 press conference. He said, in retrospect, given the choice between winning a second term or founding the Carter Center, he would have chosen the Carter Center. The well-funded and globally respected nonprofit will carry his work and ideals well into the future. The Carters dived — freelance and sometimes to the chagrin of the White House — into brokering peace between warring groups, addressing global health, shoring up human rights, freeing hostages, spreading democracy and increasing food production. It led to a passel of recognitions and awards — including his 2002 Nobel Peace Prize. The idea for the center came to him in a night-time dream of cabins built on a patch of wooded land, incongruously, within the shadows of Atlanta’s skyline, Carter told the AJC. His center was to be a re-creation of the wooded presidential retreat at Camp David, the location where he orchestrated, through stubborn refusal to accept “no” from either side, the Israel-Egypt Peace Treaty. He found a patch of land east of downtown, but he had to plead with his former United Nations Ambassador Andrew Young, who was then mayor of Atlanta, to spare the land from a proposed highway project. The Israel-Egypt peace deal was a foreign-policy coup in the Mideast that no one has come close to replicating, and Carter’s hopes of re-creating the highlight of forging peace between implacable enemies grew into the ever-evolving Atlanta institution. The Carters wrestled with what the center’s other roles should be before turning to their personal experiences with poverty in south Georgia during the Great Depression. They recalled small-town values of neighborly help and their deeply held Christian values and applied those to Carter Center work. At the center’s founding, his work focused on mediating peace between warring groups, such as helping end a conflict between Ethiopia and its breakaway region of Eritrea. “And we still do some of that,” Carter said, but the focus of the center’s work changed and shifted with world need. They looked for causes few others were working on and used their status to leverage donations and attention, ultimately tipping the balance in battles against various human ills. The Carters’ work moved into fostering democracy by monitoring national and village level elections. Carter and his staff monitored more than 113 elections in 39 countries. As president, he helped normalize relations with China, and its government invited him in the 1990s to help standardize the vast array of electoral procedures in rural areas. The Carters adopted mental health issues, something Rosalynn had worked on since their days in the Georgia governor’s mansion, as well as press freedoms, human rights and government transparency. They threw themselves into food production programs in African villages, something Carter had worked on as president. But it was a visit from an old Georgia friend and former White House staffer Dr. Peter Bourne that opened the former president’s eyes to the issues on which a lion’s share of Carter Center money is spent: the eradication of little-known but devastating diseases. Bourne continued working on world health issues after leaving the White House, but the former president had him come to the Carter Center in May 1985 to talk about Guinea worm disease. Bourne and others believed it could be wiped out, which would make it the second human disease in history to be eliminated, after smallpox. Later that year, Bourne and the Carters were together in Wales indulging in one of their favorite pastimes, fishing. Bourne told them that others had some success eradicating Guinea worm at local levels in Africa and south Asia, where about 3.5 million people were affected. They knew that once the parasitic, water-born cycle was broken, it would be wiped from the earth. But those working on it didn’t have the political clout to convince countries to get involved at the highest levels. Carter could bring that, Bourne told them. Carter thought about it a few weeks, then called Bourne to say he was in. “He has been the driving force in getting the political will necessary ever since,” Bourne said. With Carter raising the profile of the illness and money — the center’s assets were more than $925 million according to its 2020 annual report — governments and nonprofits got behind it. Guinea worm was down to 14 reported cases in 2021 in four African countries, the center said. “We analyzed every human illness on earth to ascertain which ones of those might theoretically be ... eradicated,” Carter said. And they chose four others in addition to Guinea worm. River blindness was found in Africa and parts of Central and South America. By 2015, the center’s work coordinating nonprofits and governments pushed the disease into a few isolated deep-jungle spots in Venezuela and Brazil. With a great deal of optimism, the center moved in 2014 to declare a war on eradication of river blindness in Africa, where more than 100 million people are at risk. The center also began programs for trachoma, an infectious eye disease causing blindness; two diseases carried by parasitic worms, elephantiasis and schistosomiasis; and malaria in the Caribbean. The center will carry the couple’s work well past their demise. “I think 100 years from now we will still have the Carter Center as an independent entity,” Carter said. “I hope they are still doing the kinds of good things we have done so far.” ©2024 The Atlanta Journal-Constitution. Visit at ajc.com . Distributed by Tribune Content Agency, LLC.

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WASHINGTON — American Airlines briefly grounded flights nationwide Tuesday because of a technical problem just as the Christmas travel season kicked into overdrive and winter weather threatened more potential problems for those planning to fly or drive. Government regulators cleared American flights to get airborne about an hour after the Federal Aviation Administration ordered a national ground stop for the airline. The order, which prevented planes from taking off, was issued at the airline's request. The airline said in an email that the problem was caused by trouble with vendor technology that maintains its flight operating system. An American Airlines employee wearing looks toward quiet check-in counters Tuesday in the American terminal at Miami International Airport in Miami. Dennis Tajer, a spokesperson for the Allied Pilots Association, a union representing American Airlines pilots, said the airline told pilots at 7 a.m. Eastern that there was an outage affecting the system known as FOS. It handles different types of airline operations, including dispatch, flight planning, passenger boarding, as well as an airplane's weight and balance data, he said. Some components of FOS have gone down in the past, but a systemwide outage is rare, Tajer said. Flights were delayed across American's major hubs, with only 37% leaving on time, according to Cirium, an aviation analytics company. Out of the 3,901 domestic and international American Airlines flights scheduled for Tuesday, 19 were canceled. Cirium noted that the vast majority of flights departed within two hours of their scheduled departure time. A similar percentage — 36% — arrived at their destinations as scheduled. Meanwhile, the flight-tracking site FlightAware reported that 3,712 flights entering or leaving the U.S., or serving domestic destinations, were delayed Tuesday, with 55 flights canceled. It did not show any flights from American Airlines. Cirium said Dallas-Fort Worth, New York's Kennedy Airport and Charlotte, North Carolina, saw the greatest number of delays. Washington, Chicago and Miami experienced considerably fewer delays. Travelers wait in line for security checks Tuesday at the Los Angeles International Airport in Los Angeles. Amid the travel problems, significant rain and snow were expected in the Pacific Northwest at least into Christmas Day. Showers and thunderstorms developed in the South. Freezing rain was reported in the Mid-Atlantic region near Baltimore and Washington, and snow fell in New York. Because the holiday travel period lasts weeks, airports and airlines typically have smaller peak days than they do during the rush around Thanksgiving, but the grind of one hectic day followed by another takes a toll on flight crews. Any hiccups — a winter storm or a computer outage — can snowball into massive disruptions. That is how Southwest Airlines stranded 2 million travelers in December 2022, and Delta Air Lines suffered a smaller but significant meltdown after a worldwide technology outage in July caused by a faulty software update from cybersecurity company CrowdStrike. Many flights during the holidays are sold out, which makes cancellations even more disruptive than during slower periods. That is especially true for smaller budget airlines that have fewer flights and fewer options for rebooking passengers. Only the largest airlines, including American, Delta and United, have "interline agreements" that let them put stranded customers on another carrier's flights. An American Airlines employee wearing a Santa Claus hat walks through the American terminal Tuesday at Miami International Airport in Miami. This will be the first holiday season since a Transportation Department rule took effect that requires airlines to give customers an automatic cash refund for a canceled or significantly delayed flight. Most air travelers were already eligible for refunds, but they often had to request them. Passengers still can ask to get rebooked, which is often a better option than a refund during peak travel periods. Finding a last-minute flight on another airline tends to be expensive. An American spokesperson said Tuesday was not a peak travel day for the airline — with about 2,000 fewer flights than the busiest days — so the airline had somewhat of a buffer to manage the delays. The groundings happened as millions of travelers were expected to fly over the next 10 days. The Transportation Security Administration expects to screen 40 million passengers through Jan. 2. Airlines expect to have their busiest days on Thursday, Friday and Sunday. American Airlines employees check in travelers Tuesday in the American terminal at Miami International Airport in Miami. Many flights during the holidays are sold out, which makes cancellations more disruptive than during slower periods. Even with just a brief outage, the cancellations have a cascading effect that can take days to clear up. About 90% of Americans traveling far from home over the holidays will be in cars, according to AAA. "Airline travel is just really high right now, but most people do drive to their destinations, and that is true for every holiday," AAA spokesperson Aixa Diaz said. Gasoline prices are similar to last year. The nationwide average Thursday was $3.04 a gallon, down from $3.13 a year ago, according to AAA. Charging an electric vehicle averages just under 35 cents per per kilowatt hour, but varies by state. Transportation-data firm INRIX says travel times on the nation's highways could be up to 30% longer than normal over the holidays, with Sunday expected to see the heaviest traffic. "It's not the destination, it's the journey," said American essayist Ralph Waldo Emerson. Ralph clearly was not among the travellers on one of more than 350 cancelled or 1,400 delayed flights after a worldwide tech outage caused by an update to Crowdstrike's "Falcon Sensor" software in July of 2023. U.S. airlines carried nearly 863 million travellers in 2023, with Canadian carriers accounting for another 150 million, many of whom experienced lost luggage, flight delays, cancellations, or were bumped off their flights. It's unclear how many of them were compensated for these inconveniences. Suffice it to say, posting a crabby rant on social media might temporarily soothe anger, but it won't put wasted money back in pockets. Money.ca shares what to know in order to be compensated for the three most common air travel headaches. Bags elected to go on a vacay without you? Check off the following: If you expect a large payout, think again. Tariffs (air carrier contracts) limit the compensation amounts for "loss of, damage to, or the delay in delivery of baggage or other personal property." In the case of Air Canada, the maximum payout is $1,500 per passenger in the currency of the country where the baggage was processed. To raise that limit, purchase a Declaration of Higher Value for each leg of the trip. The charge is $0.50 for each $100, in which case the payout limit is $2,500. For Delta Air Lines, passengers are entitled to up to $3,800 in baggage compensation, though how much you'll receive depends on your flight. Delta will pay up to $2,080 for delayed, lost, and damaged baggage for international travellers, almost half of what U.S. domestic passengers can claim. If your flight is marked delayed for more than 30 minutes, approach the gate agent and politely request food and hotel vouchers to be used within the airport or nearby. Different air carriers and jurisdictions have their own compensation policies when flights are delayed or cancelled. For example, under European Union rules, passengers may receive up to 600 Euros, even when travelling on a non-EU carrier. Similarly, the DOT states that travellers are entitled to a refund "if the airline cancelled a flight, regardless of the reason, and the consumer chooses not to travel." However, US rules regarding delays are complicated. Some air carriers, such as Air Canada, do not guarantee their flight schedules. They're also not liable for cancellations or changes due to "force majeure" such as weather conditions or labour disruptions. If the delay is overnight, only out-of-town passengers will be offered hotel accommodation. Nevertheless, many airlines do offer some compensation for the inconvenience. If your flight is marked delayed for more than 30 minutes, approach the gate agent and politely request food and hotel vouchers to be used within the airport or nearby. In terms of cash compensation, what you'll get can differ significantly based on things like departure location, time, carrier, and ticket class. The DOT offers a helpful delay and cancellations dashboard designed to keep travellers informed about their compensation rights. The dashboard is particularly helpful because, as the DOT states on its website, "whether you are entitled to a refund depends on a lot of factors—such as the length of the delay, the length of the flight, and your particular circumstances." The Canadian Transportation Agency is proposing air passenger protection regulations that guarantee financial compensation to travellers experiencing flight delays and cancellations, with the level of compensation varying depending on the situation and how much control the air carrier had. The proposed regulations include the following: The airline is obligated to complete the passenger's itinerary. If the new ticket is for a lower class of service, the air carrier would have to refund the cost difference; if the booking is in a higher class of service, passengers cannot be charged extra. If the passenger declines the ticket, the airline must give a full refund, in addition to the prescribed compensation. For overnight delays, the air carrier needs to provide hotel accommodation and transportation free-of-charge. Again, if you are unsatisfied, the Canadian Transportation Agency or Department of Transportation may advocate on your behalf. Passengers get bumped because airlines overbook. When this happens, the air carrier must compensate you. For international flights in the US, the rate is 200% of your one-way fare to your final destination, with a $675 maximum. If the airline does not make travel arrangements for you, the payout is 400% of your one-way fare to a maximum of $1,350. To qualify, you must check-in by the stated deadline, which on international flights can be up to 3 hours ahead. Keep in mind that if you accept the cash, you are no longer entitled to any further compensation, nor are you guaranteed to be rebooked on a direct flight or similar type of seat. Don't be too quick to give up your boarding pass. Negotiate for the best compensation deal that would include cash, food and hotel vouchers, flight upgrade, lounge passes, as well as mileage points. But avoid being too greedy—if the gate attendant is requesting volunteers and you wait too long, you'll miss the offer. According to Air Canada's tariff, if a passenger is involuntarily bumped, they'll receive $200, in cash or bank draft, for up to a two-hour delay; $400 for a 2-6 hours delay; and $800 if the delay is over six hours. (Air Canada was forced to raise its payouts in 2013 due to passenger complaints.) The new rules would raise the payout significantly: $900 for up to six hours; $1,800 for 6-9; and $2,400 for more than nine hours, all to be paid within 48 hours. Statistically speaking, Delta Airlines is the carrier most likely to bump. A few years ago, Delta raised its payout maximum to $9,950, while United Airlines tops out at $10,000. This story was produced by Money.ca and reviewed and distributed by Stacker. Get local news delivered to your inbox!Claro Enterprise Solutions Expands Technology Service Offerings to Accelerate Mergers and Acquisitions Integrations

2024 was another banner year for a source of electricity that is better for people’s lungs, better for climate change and may be reaching your home when you turn on the lights or turn up the thermostat — large banks of batteries. This ability to store large amounts of electricity in batteries was essentially nonexistent a decade ago, but the country had about 24 gigawatt-hours operating as of the end of November, up a whopping 71% over the same date in 2023. This is welcome news to clean energy advocates including Dariella Rodriguez. She has seen what happens on days when demand for air conditioning or heating spikes and extra power plants fueled by natural gas, located in Port Morris and Mott Haven, fire up not far from where she works in Hunts Point in the South Bronx, New York. Batteries can jolt into service, sending electricity onto overhead wires, instead of these dirty “peaker” plants. Rodriguez hasn’t seen that transition yet, but she hopes to. “The people that are exposed to these plants are the most vulnerable people in environmental justice communities already,” said Rodriguez, a director at THE POINT Community Development Corporation there, noting that lower-income people and communities of color often live near peakers. The nation’s 1,000 peaker plants can be very dirty, inefficient and expensive, according to an analysis by the U.S. Government Accountability Office, a watchdog group that works for the U.S. Congress. Some 63 million people are estimated to live within a three-mile radius of one. Although peakers run only a small part of the time, they release more harmful nitrogen oxides and sulfur dioxide per unit of energy, the agency said. Those two pollutants cause asthma and other breathing problems. Peakers also release more greenhouse gases than other power plants do per unit of electricity. Batteries are “a really obvious solution” to reducing need for peakers, says Daniel Chu, senior energy planner for the New York City Environmental Justice Alliance. Storing extra power in batteries also extends the hours of the day that you can use clean energy. “It’s not always sunny, the wind’s not always blowing, but energy storage can help move that generation to when it’s most needed,” said Tim Fox, managing director at research firm ClearView Energy Partners. That’s why at least half of battery storage facilities in the U.S. are co-located with, or in some other way support solar, an AP analysis of Energy Information Administration data shows. The amount of solar energy in the U.S. is growing and surpassed the 100-gigawatt mark this year. Another way that the addition of these batteries is helpful to the American electrical grid and grids around the world is that forecasting is getting more difficult. “With weather patterns changing, the old ways of essentially figuring out how much capacity you need on the grid for extreme events just doesn’t work,” said Oliver Garnett, director of energy services product at the technology company Fermata Energy. Last, global electricity demand is slated to increase — by about one-third to three-quarters by 2050, according to the Energy Information Administration . Data centers for artificial intelligence, switching vehicles to electricity and population growth are all contributing. “‘Do we have enough power plants?’ is the classic question every utility asks every year,” said Mike Jacobs, senior energy analyst at the science nonprofit Union of Concerned Scientists. “The beauty of the batteries is that if there’s energy in them, they can be used for unexpected needs.” Otherwise, if utilities have to find more power generation, they may keep investing in plants that burn gas or coal and account for one-quarter of the nation’s greenhouse gas emissions , instead of retiring them. Leading the charge for adding new batteries to the grid this year was California with more than 11 gigawatt-hours operating. One way to think about this is roughly the amount of electricity that a nuclear power plant would put out over 11 hours. Then the batteries would need to be recharged to do the same thing again. It’s a limited, but meaningful amount of power. In Texas, 6 gigawatt-hours were online. Arizona saw nearly 2 gigawatt-hours humming and Nevada — the fourth-largest deployer of storage in the U.S. — had 1.1 gigawatt-hours operational. Yet many states aren’t using storage yet. As of November, 86% of large-scale battery storage in the U.S. was operating in just those four states. Some states haven’t set targets telling utilities to go out and build or buy energy storage on their own. Only 18 states have 50 megawatt-hours or more operating. Others don’t have as much clean electricity to pair with the batteries, or claim storage isn’t reliable in times of crisis. It can also be challenging to connect storage to the grid. Still, experts expect more momentum. Especially in California and Texas, “That investment and that experiment is paying off very well,” said John Hensley, senior vice president of markets and policy analysis at American Clean Power. “The word is getting out,” he said. “We’re increasingly seeing the technology move to other parts of the country.”

Evaluating strategic options for iopofosine I 131 a late-stage clinical program with compelling Phase 2 data and a substantial market opportunity Focusing on advancing radiotherapeutic assets including alpha- and Auger-emitting radioconjugates into Phase 1 solid tumor studies FLORHAM PARK, N.J., Dec. 10, 2024 (GLOBE NEWSWIRE) -- Cellectar Biosciences, Inc. (NASDAQ: CLRB), a late-stage clinical biopharmaceutical company focused on the discovery, development and commercialization of drugs for the treatment of cancer, today announces a strategic update on its clinical development programs for its proprietary phospholipid ether drug conjugate platform that delivers a broad array of therapeutic modalities to target cancers. Due to recent communications with the U.S. Food and Drug Administration (FDA, or the Agency) regarding a confirmatory study to support accelerated approval and the regulatory submission for iopofosine I 131, the Company has decided to pursue strategic options for the further development and commercialization of this product candidate. The CLOVER-WaM study was conducted in accordance with earlier FDA communications from an end of Phase 2 meeting and from a meeting in early 2024, during which the Company was informed that positive results for major response rate (MRR) as the primary endpoint could be acceptable to support accelerated approval of iopofosine I 131 as a treatment for Waldenstrom’s macroglobulinemia (WM). Based upon a recent Type-C meeting with the FDA, the Company now believes that a submission seeking accelerated approval would need to be based on the MRR data from CLOVER-WaM and enrollment in a randomized, controlled confirmatory study that is designed to generate data on progression-free survival (PFS). “While iopofosine I 131’s positive WM data along with the high unmet medical need for these patients support further investment, we have determined that such a program may best be brought to market by a larger organization with greater resources. Importantly, partnering or divesting this program supports our commitment to providing this potentially life-saving drug to the patients who need it as quickly as possible,” stated James Caruso, president and CEO of Cellectar. “We believe iopofosine I 131 represents a compelling opportunity as it has shown strong efficacy and good tolerability based on our clinical studies. Moreover, the commercial work we conducted demonstrates iopofosine I 131’s substantial market opportunity based upon the product profile, which includes off-the-shelf global distribution, orphan pricing and existing unmet medical need.” Cellectar remains confident in the potential of its phospholipid ether drug conjugate platform and the targeted radiotherapies in its development pipeline. Iopofosine I 131’s clinical success validates the platform’s ability to target cancers and Cellectar will leverage its experience to focus on the development of its earlier clinical programs. Specifically, Cellectar will focus on those assets it believes have the highest therapeutic potential and opportunity for value creation. As highlighted by recent acquisitions and collaborations within the radiopharmaceutical sector, precision isotopes like alpha- and Auger-emitters have emerged as the leading therapeutics of interest. Consequently, the Company will now focus its resources on targeting solid tumors by advancing CLR 121225, its actinium-225 based program, and CLR 121125, its iodine-125 Auger-emitting program into the clinic. Cellectar expects to file Investigational New Drug applications in the first half of 2025 for both CLR-121225 and CLR-121125, which will allow the initiation of Phase 1 clinical studies in solid tumor cancers. Both programs have demonstrated robust in vivo activity, tolerability, excellent targeting and uptake in preclinical solid tumor models. The Company believes this approach will provide an expedited timeframe to achieve safety and proof-of-concept data in patients. The Company’s strategic reprioritization will impact all departments and result in an immediate reduction in headcount of approximately 60%, which should be complete by the end of the fourth quarter 2024. The Company anticipates that the implementation of the restructuring will extend its cash runway into the third quarter of 2025. “We are being methodical in our efforts to reorganize the company with the goal of conserving cash while maintaining the flexibility to execute immediate priorities and build for long-term growth and value creation. This reorganization is difficult but necessary for the future growth potential of Cellectar,” said Mr. Caruso. “I want to extend my deepest gratitude to our departing employees for their significant contributions to our work and their dedication to making a difference in the lives of patients.” About Cellectar Biosciences, Inc. Cellectar Biosciences is a late-stage clinical biopharmaceutical company focused on the discovery and development of proprietary drugs for the treatment of cancer, independently and through research and development collaborations. The company’s core objective is to leverage its proprietary Phospholipid Drug Conjugate TM (PDC) delivery platform to develop the next-generation of cancer cell-targeting treatments, delivering improved efficacy and better safety as a result of fewer off-target effects. The company’s product pipeline includes lead asset, iopofosine I 131, a small-molecule PDC designed to provide targeted delivery of iodine-131 (radioisotope), CLR 121225, an actinium-225 based program being targeted to several solid tumors with significant unmet need, such as pancreatic cancer, CLR 121125, an iodine-125 Auger-emitting program targeted in other solid tumors, such as triple negative breast, lung and colorectal, proprietary preclinical PDC chemotherapeutic programs and multiple partnered PDC assets. In addition, iopofosine I 131 is under evaluation in Phase 2b studies for relapsed or refractory multiple myeloma (MM) and central nervous system (CNS) lymphoma, alongside the CLOVER-2 Phase 1b study, targeting pediatric patients with high-grade gliomas, for which Cellectar is eligible to receive a Pediatric Review Voucher from the FDA upon approval. The FDA has also granted iopofosine I 131 Orphan Drug and Fast Track Designations for various cancer indications. New data from the CLOVER-WaM Phase 2 clinical trial were recently presented in an oral presentation at the 66th American Society of Hematology Annual Meeting and Exposition (ASH 2024). For more information, please visit www.cellectar.com or join the conversation by liking and following us on the company’s social media channels: Twitter, LinkedIn, and Facebook. Forward-Looking Statement Disclaimer This news release contains forward-looking statements. You can identify these statements by our use of words such as "may," "expect," "believe," "anticipate," "intend," "could," "estimate," "continue," "plans," or their negatives or cognates. These statements are only estimates and predictions and are subject to known and unknown risks and uncertainties that may cause actual future experience and results to differ materially from the statements made. These statements are based on our current beliefs and expectations as to such future outcomes. Drug discovery and development involve a high degree of risk. Factors that might cause such a material difference include, among others, uncertainties related to the ability to raise additional capital, uncertainties related to the disruptions at our sole source supplier of iopofosine, the ability to attract and retain partners for our technologies, the identification of lead compounds, the successful preclinical development thereof, patient enrollment and the completion of clinical studies, the FDA review process and other government regulation, our ability to obtain regulatory exclusivities, the availability of priority review vouchers, our ability to successfully develop and commercialize drug candidates, competition from other pharmaceutical companies, product pricing and third-party reimbursement. A complete description of risks and uncertainties related to our business is contained in our periodic reports filed with the Securities and Exchange Commission including our Form 10-K/A for the year ended December 31, 2023, and our Form 10-Q for the quarter ended September 30, 2024. These forward-looking statements are made only as of the date hereof, and we disclaim any obligation to update any such forward-looking statements. Contacts MEDIA: Christy Maginn Bliss Bio Health 703-297-7194 cmaginn@blissbiohealth.com INVESTORS: Anne Marie Fields Precision AQ 212-362-1200 annemarie.fields@precisionaq.comKhurshid Ganai red flags environmental issues in KashmirNEW YORK — No ex-president had a more prolific and diverse publishing career than Jimmy Carter . His more than two dozen books included nonfiction, poetry, fiction, religious meditations and a children’s story. His memoir “An Hour Before Daylight” was a Pulitzer Prize finalist in 2002, while his 2006 best-seller “Palestine: Peace Not Apartheid” stirred a fierce debate by likening Israel’s policies in the West Bank to the brutal South African system of racial segregation. And just before his 100th birthday, the Dayton Literary Peace Prize Foundation honored him with a lifetime achievement award for how he wielded "the power of the written word to foster peace, social justice, and global understanding.” In one recent work, “A Full Life,” Carter observed that he “enjoyed writing” and that his books “provided a much-needed source of income.” But some projects were easier than others. “Everything to Gain,” a 1987 collaboration with his wife, Rosalynn, turned into the “worst threat we ever experienced in our marriage,” an intractable standoff for the facilitator of the Camp David accords and winner of the Nobel Peace Prize. According to Carter, Rosalynn was a meticulous author who considered “the resulting sentences as though they have come down from Mount Sinai, carved into stone.” Their memories differed on various events and they fell into “constant arguments.” They were ready to abandon the book and return the advance, until their editor persuaded them to simply divide any disputed passages between them. “In the book, each of these paragraphs is identified by a ‘J’ or an ‘R,’ and our marriage survived,” he wrote. Here is a partial list of books by Carter: “Keeping Faith: Memoirs of a President” “The Blood of Abraham: Insights into the Middle East” (With Rosalynn Carter) “Everything to Gain: Making the Most of the Rest of Your Life” “An Outdoor Journal: Adventures and Reflections” “Turning Point: A Candidate, a State, and a Nation Come of Age” “Always a Reckoning, and Other Poems” (With daughter Amy Carter) “The Little Baby Snoogle-Fleejer” “Living Faith” “The Virtues of Aging” “An Hour Before Daylight: Memories of a Rural Boyhood” “Christmas in Plains: Memories” “The Hornet’s Nest: A Novel of the Revolutionary War” “Our Endangered Values: America’s Moral Crisis” “Faith & Freedom: The Christian Challenge for the World” “Palestine: Peace Not Apartheid” “A Remarkable Mother” “Beyond the White House” “We Can Have Peace in the Holy Land: A Plan That Will Work” “White House Diary” “NIV Lessons from Life Bible: Personal Reflections with Jimmy Carter” “A Call to Action: Women, Religion, Violence, and Power” “A Full Life: Reflections at Ninety”

Yuval Noah Harari, the guy who makes history and future cool, suggests must-read books that shine a light on Africa 's rich history. These books span millennia, providing a deep dive into the continent's vibrant cultures, groundbreaking innovations, and profound global impact. Harari's picks offer a multi-faceted exploration of African history, from the dawn of civilization to the modern era. 'Guns, Germs, and Steel' Jared Diamond's Guns, Germs, and Steel is a landmark book that answers the question of how the environment shaped the world. Focusing on Africa's rich ecosystems and geographical complexities, Diamond delves into how these factors shaped societies and their interactions with other continents. This book gives you a comprehensive understanding of how Africa's unique environment influenced its history. 'The Fate of Africa' Martin Meredith's The Fate of Africa provides a comprehensive account spanning 50 years of post-colonial history. It shines a light on the hopes and realities of African nations as they emerged from colonial rule and grappled with independence in a rapidly changing world order. Meredith's work serves as a bridge, fostering a deeper understanding of the modern African states, their evolution, and the dreams that have shaped them. 'Africa: A Biography of the Continent' John Reader's Africa: A Biography of the Continent is a journey back in time to the very cradle of humanity. This book weaves together archaeological discoveries and historical analysis to paint a vivid picture of human evolution and the dawn of civilization in Africa. Reader's work is a must-read for anyone curious about the deep-rooted past that has shaped the modern tapestry of African societies. 'The State in Africa: The Politics of the Belly' Jean-Francois Bayart's The State in Africa: The Politics of the Belly is a groundbreaking analysis of the role of personal networks in African governance. It provides a deep understanding of both historical and contemporary political dynamics, focusing on the importance of personal relationships. This book is essential reading for anyone seeking to understand African politics beyond Western frameworks, shedding light on the continent's distinct political reality.Survey on isolation: Nearly half of Minnesotans report feeling left out at times

ROHM and TSMC Launch Strategic Gallium Nitride Technology Collaboration for the Automotive IndustryWall St indexes fall, inflation data and rates in focusThe price of Binance Coin (BNB) skyrocketed and crossed the $750 mark, with its market cap exceeding $100 million. As investors are excited about this development, a new contender comes under the spotlight. IntelMarkets (INTL) is one of the most promising projects featuring an emerging platform of decentralized finance (DeFi) and artificial intelligence (AI). Raising more than $2.8 million, INTL's presale is one of the fastest-growing prospects this year. BNB's ATH Suffers Pull Back After Surpassing Key Resistance BNB, the native cryptocurrency of Binance, has been one of the biggest players in the cryptocurrency market. On 4 December 2024, BNB reached an all-time close of $793.35 as a result of growing interest from investors and Bitcoin's rally to $100k. This peak, however, has come down, as the BNB price dropped to $754.06, dropping 3.39% in the last 24 hours. But the token's momentum stalled after some profit taking and broader market retracements pushed prices back from the peak. Although this is a temporary setback, the strong fundamentals behind Binance coupled with the increased utility of the Binance Smart Chain have made it a major force in the decentralized finance (DeFi) space. This increase in investor interest for projects in the DeFi scene has prompted a new contender to rise. IntelMarkets (INTL): A New Contender in the Crypto Market IntelMarkets (INTL) is a trading platform that offers revolutionary futures that combine AI, blockchain technology and DeFi. IntelMarkets utilizes AI to provide users unprecedented computing power and self-learning trading robots that analyze enormous numbers of data continuously in real-time. The real value of INTL is in the AI-driven insights that provide traders the best trading strategies available. One testament to the success of IntelMarkets is the 7x price surge INTL tokens experienced since launch. Currently in the seventh presale stage, IntelMarkets raised more than $2.8 million with tokens trading at $0.065 apiece. The dual-chain architecture of the platform supports Solana and Ethereum blockchains making it fast and scalable. Comparing BNB and IntelMarkets (INTL) BNB has become one of the most popular cryptocurrencies. Binance is the number one centralized exchange (CEX), dominating the market with a $34 billion trading volume. Analysts claim that with the growing adoption of Binance, the BNB coin would proportionally rise. However, its growth potential may be limited because of its $104 billion market capitalization. On the contrary, IntelMarkets offers an innovative AI-DeFi story together with a low market cap. With the growing rise of AI based tokens on Binance, a listing on the exchange could propel IntelMarkets to the next level. According to experts, INTL could have a 15x rally post-launch, which makes IntelMarkets an excellent alternative investment for maximizing profits. IntelMarket’s Binance Listing Could Ignite 15x Rally Recent fluctuations in the price of BNB shows how dynamic the market of cryptocurrencies is. IntelMarkets (INTL) is one investment for investors looking for opportunities with high growth potential. Designing an AI product into DeFi offers an innovative solution to crypto trading, INTL is one of the most promising presales ahead of 2025. Learn More about IntelMarkets: Buy Presale Website Telegram Join our WhatsApp Channel to get the latest news, exclusives and videos on WhatsApp _____________ Disclaimer: Analytics Insight does not provide financial advice or guidance. Also note that the cryptocurrencies mentioned/listed on the website could potentially be scams, i.e. designed to induce you to invest financial resources that may be lost forever and not be recoverable once investments are made. You are responsible for conducting your own research (DYOR) before making any investments. Read more here.

Based on the first 35 minutes, few people in the building could have predicted the final outcome. It was the second game of back-to-back contests between the Soo Greyhounds and Windsor Spitfires at the GFL Memorial Gardens. With the Greyhounds leading 2-1 and five minutes to go in the second period, the Spitfires scored four times before the period was over and ultimately picked up a 10-6 win over the Greyhounds. For the Greyhounds, it was a learning experience for their young players after getting blanked by the Spitfires on Saturday night. “Yesterday was compete, effort, decision-making (issues),” Greyhounds coach John Dean said. “Today were mistakes that (can be) corrected and have our guys learn from.” Dean also chose to reflect on some of the positives in the game. “As a team, we scrapped all 60 and find a way to get back into it, which was super impressive,” Dean said. “I talked to the guys yesterday about being a process-oriented team and how wins and losses are important, but how you win and lose is also important. Tonight, it’s tough not to be proud of the group of 20. We give ourselves a chance to come back and win a game that, for tough reasons, I thought we shouldn’t have been out of.” Dean also called the game one in which “it seemed like every mistake we made went in the back of our net.” For Spitfires coach Greg Walters, the way the Greyhounds started the game was tough on Windsor. “They came out very hungry starting the game. They definitely outworked us,” Walters said. Walters added that the Spitfires scoring a late goal in the final minute of the opening period and then proceeding to score four times in the final 4:24 of the second period “are gamebreakers.” “Our talent came through,” Walters also said of the stretch. “When (Windsor’s) third goal goes in (23 seconds later), there’s some details we missed on that and experienced teams get that puck in deep right after and go to work,” Dean said when asked if things tend to snowball for young teams when shorthanded. “I do think experienced teams get that puck in deep and go to work.” Walters credited the Greyhounds for coming back and making the game close as well in the third period after the visitors had appeared to break the game open. “Their team never quits,” Walters said. “Even when it got to 7-3, they kept coming and working and made it a game. We were fortunate to get some big goals from some of our big time guys.” Walters added that the game was partially a case of the Spitfires finding a way to win despite not necessarily playing well. “We talk about good teams finding a way to win when you’re not playing at your best and that was definitely the case tonight,” Walters said. The Greyhounds opened the scoring as Jordan Charron got the puck from Carson Andrew and beat Windsor goaltender Jake Windbiel from the right circle at 13:12 of the opening period. Windsor tied the game in the final minute of the period as Ryan Abraham beat Landon Miller from the left circle after the Sault goaltender stopped a shot from the right circle by Cole Davis initially. Travis Hayes gave the Greyhounds a 2-1 lead at 9:37 of the second period as he took a breakaway pass from Keegan Gillen and beat Windbiel glove side. Windsor tied the game again as Jean-Christophe Lemieux took a cross-ice pass from Liam Greentree and beat Miller high short side from the left circle at 15:36. On the next shift, Davis gave Windsor the lead by converting a cross-ice pass in the right circle from Noah Morneau, beating Miller glove side on the play at 15:59. Morneau then beat Miller from the slot after a pass by Jack Nesbitt was partially blocked and ended up on Morneau’s stick. The goal came with 1:30 to go in the period. In the final seconds of the middle period, Laim Greentree made it a 5-2 game as he took a pass in the left circle from Ethan Garden and beat Miller. Windsor extended the lead as Nesbitt beat Miller with a shot from the left win while much of the focus was on an altercation between Greentree and Hayes at the other end of the ice 3:05 into the third period. Jsutin Cloutier made it 6-3 just 55 seconds later as he beat Windbiel with a shot from the right faceoff circle. Windsor’s Ilya Protas continued the scoring barrage as he took a pass from A.J. Spellacy and beat Miller at 6:45 of the third to make it a 7-3 game. The Greyhounds pulled back to within three at 7:48 as a shot from the high slot by Owen Allard beat Windbiel after getting deflected by Marco Mignosa. The home team pulled to within two at 8:26 as Hunter Solomon beat Windbiel with a shot from the top of the right faceoff circle and then made it a one-goal game as Allard beat Windbiel through traffic with a shot from the high slot at 14:45. Greentree added on to the Spitfires lead at 17:40 as he took a pass from Conor Walton and beat Miller stick side to make it an 8-6 game. Windsor added a pair of late goals to cap off the scoring as Davis grabbed a Greyhounds turnover as Miller was coming out for an extra attacker and scored as the Sault netminder tried to scramble back into the goal with 2:02 to go and potted his third of the night in the final minute of action. Allard and Cloutier had a goal and an assist each for the Greyhounds in the loss while Andrew, Chase Reid, and Erik Muxlow assisted on two goals each. Miller stopped 20 shots for the Greyhounds. Davis finished the day with four points (three goals and an assist) for Windsor. Greentree had two goals and an assist for the Spitfires while Protas also had a three-point day with a goal and two assists. Nesbitt, Abraham, and Morneau had a goal and an assist each. Ethan Garden assisted on a pair of Windsor goals. Windbiel stopped 32 shots. The Greyhounds now have some time off before returning to action at home on Friday night when they host the Peterborough Petes. The Greyhounds will take a 15-20-0-0 record into that game. With the win, Windsor improves to 25-7-2-1 on the season, Rookie forward Ethan Belchetz missed Sunday’s game after receiving a major penalty for checking to the head in Saturday night’s contest. In the opening minute of the third period, Belchetz hit Greyhounds defenceman Spencer Evans along the end boards in the Sault zone. Evans was injured on the play and missed Sunday’s game. For Evans, it was his first game back after sitting out a month due to a previous injury. Dean said the blueliner is out day-to-day at this point. Brady Martin missed his third consecutive game for the Greyhounds on Sunday due to an injury and remains out. Chrstopher Brown also remains out due to injury. Initially injured on Nov. 8 in Kitchener, Brown sat out four games before returning to the lineup on Nov. 21 against Niagara. The veteran forward was reinjured and has been out since, a stretch of 12 games. Brown skated on his own prior to Sunday’s game.Mumbai: The Supreme Court’s interim order barring the Enforcement Directorate (ED) from unlocking and examining electronic devices seized from Santiago Martin has stirred significant concerns among investigative agencies. The decision has sparked debates on privacy rights and its potential implications on ongoing and future investigations. The apex court's intervention follows a petition filed by Future Gaming, which seeks to protect fundamental rights, particularly the right to privacy. The petition argues that the information stored on personal digital devices is highly personal and intimate, necessitating safeguards against unrestricted access. The court has explicitly directed the ED “not to access and copy” the content of mobile phones belonging to lottery king Santiago Martin, who heads Future Gaming, and a range of electronic devices belonging to his company’s employees. The ED, which is investigating Santiago Martin in connection with alleged money laundering activities involving large sums, has expressed disappointment over the order. A senior official, speaking on the condition of anonymity, stated that it won’t impact their case as they have strong evidence against Martin. but acknowledged it as a "major obstacle" in obtaining crucial digital data. Officials have also raised concerns that the Supreme Court’s decision could set a challenging precedent for ongoing and future cases. If accused individuals routinely challenge the seizure of electronic devices, it could hamper our ability to gather critical digital evidence, especially in cases involving financial fraud and money laundering. Advocate Adity Talpade, representing several accused in CBI and DRI cases, commented, "The Supreme Court's recent order will positively affect numerous cases nationwide. Seizing and examining someone's mobile phone infringes on their privacy, which is integral to personal liberty and dignity. Additionally, in cases of mobile phone seizure, the hash value (a unique code representing the contents of a file or data) must be secured at the time of seizure, as required by the Information Technology Act, 2000, to ensure it is not tampered with. Advocate Viquar Rajguru, representing Mohammad Salim Qureshi alias Salim Fruit, an associate of Chhota Shakeel, said, "This is a commendable decision by the Supreme Court, affirming its historic ruling on the right to privacy in the K.S. Puttaswamy case. This decision should be welcomed, as mobile phones contain a vast amount of personal digital information." He referred to the Supreme Court's 9-judge bench decision in K.S. Puttaswamy vs. Union of India (2017) 10 SCC 1, which recognized the right to privacy as a fundamental right, describing it as a natural, basic, inherent, and inalienable right. Regarding his case, Rajguru stated that the voice sample of Salim Fruit, taken by the NIA, is under challenge before the High Court, as it was taken without proper authorization, which falls under the category of a violation of the right to privacy. However, Advocate Ejaz Nakvi argued for an appeal against the order, stating, "The Union Government should support this appeal to uphold the public's right to know the truth, which aligns with the principle of 'Satya Mev Jayate'. Santiago Martin's dubious foreign connections and offshore activities demand transparency." The case involving Future Gaming has been combined with similar petitions, including one filed by employees of Amazon India challenging the ED's demands to surrender their personal electronic devices during an investigation. This raises concerns about the scope of authority and privacy in corporate and individual contexts. Another key case in the consolidation is the Newsclick matter, where petitioners are seeking Supreme Court guidelines after the Delhi Police seized digital devices during a 2023 investigation into alleged financial irregularities. These cases collectively raise significant legal questions about the procedures, safeguards, and limits involved in seizing and accessing personal electronic data during investigations, highlighting the growing conflict between investigative powers and individual privacy rights. A senior officer from the agency stated that the procedures being followed strictly adhere to established guidelines, including the CBI Manual on Search and Seizure of Digital Evidence. The officer emphasized that the investigation is proceeding within the boundaries of the law, ensuring a balance between the needs of the investigation and respect for individual rights. Santiago Martin’s Future Gaming gained prominence recently as the single largest purchaser of now-defunct electoral bonds, having acquired bonds worth Rs 1,368 crore between 2019 and 2024. Data released by the Election Commission revealed the beneficiaries of these donations. The Trinamool Congress was the largest recipient at Rs 542 crore, followed closely by the Dravida Munnetra Kazhagam (DMK) at Rs 503 crore. Other significant recipients included the YSR Congress (Rs 154 crore) and the Bharatiya Janata Party (Rs 100 crore). Prakash Shetty, noted criminal lawyer and special public prosecutor in several terror cases, said that "No doubt personal liberty of the citizens but at the same time investigation is also necessary. The investigation cannot be controlled." However, in this case, the order passed by the Supreme court is an interim order and can be revoked or vacated if need be. The Investigating officer has to satisfy the ground and urgency for the same. "No doubt it affects the investigation and delays the process but the investigating officer has to plead the court for the necessity. Another senior public prosecutor, on the condition of anonymity said that the order hampers the investigating of the case to a greater extend. "Since the hearing is scheduled after two months, in this period lot of valuable information is lost its relevance. With the right of the accused, the court also needs to consider the rights of investigating officer who also faces pressure to complete the probe," the prosecutor said. However, he said in such cases, the officer should move and urgent plea seeking review of the order.