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Release time: 2025-01-27 | Source: Unknown
lottery prediction
lottery prediction 7 Things You Probably Didn’t Know About KimonoMonopar Announces First Patient Dosed with its Novel Therapeutic Radiopharmaceutical MNPR-101-LuRuben Amorim says he 'truly believes' Man Utd can win the Premier League

Assad's fall leaves Syria's future uncertainCalifornia politicians suddenly discover inflation in aftermath of election

Infinix Empowers Gamers as Official Gaming Phone for 2024 PMGC

The NFL said on Friday that its Week 16 game between AFC West rivals Denver Broncos and Los Angeles Chargers , both firmly in the hunt for a postseason berth, has been moved up in the schedule to be that week’s Thursday Night Football game on Prime Video . The game, at SoFi Stadium in Inglewood, will now kick off at 8:15 p.m. ET/5:15 p.m. PT on December 19. The move means the regularly scheduled TNF game that week, Cleveland at Cincinnati, will now be played Sunday, December 12 at 1 p.m. ET and air on Fox. The Chargers (7-3) under new coach Jim Harbaugh have won four games in a row heading into a Monday Night Football showdown at home against the Baltimore Ravens (8:15 p.m. ET, ABC/ESPN). Denver (6-5), plays the Las Vegas Raiders on the road Sunday. The NFL has had a deal with the networks about tweaking its schedule to ensure strong matchups and give teams a chance to play their way onto primetime schedules. Originally implemented for NBC’s Sunday Night Football programming, the flex can also be implemented for Monday Night Football , as well as TNF on a trial basis beginning this season. Amazon’s Prime Video has seen success with its TNF programming as fans become more accustomed to streaming services to find games. This is the third year of TNF on Prime Video; the schedule features 15 regular-season games including a Black Friday game pitting the Kansas City Chiefs and Raiders next week, in addition to a wild-card playoff game in January. Another streamer, Netflix, is making inroads with the NFL as well this season hosting a pair of games live on Christmas Day.

Panama president rules out talks with Trump over canal threatA Merrimack County Superior Court judge delivered an early-but-significant victory to Attorney General John Formella’s sweeping lawsuit that accuses Meta, the parent company of Facebook, Instagram and WhatsApp, of using marketing methods that mentally and physically harm young children. Lawyers for Meta had moved to dismiss the suit Formella brought last October, but denial of that motion means the five-count claim will go forward. Judge John Kissinger cited the clout of these platforms in making a critical finding that the state has “sovereign interest” and jurisdiction over Meta’s designs due to the potential impact on the mental health of young people. “13.49% of the under-eighteen population are active monthly Facebook users and 35% are active monthly Instagram users,” Kissinger wrote in a detailed 56-page ruling. “Teenagers in New Hampshire have also suffered from declining mental health since 2011. The state has an interest in protecting the mental health of its youngest population. The court sees no reason to distinguish between physical and mental health in this context.” In another key decision, Kissinger said the First Amendment gave Meta no immunity from lawsuit because the state was targeting the design of the platform and not the specific content on social media. He also decided that the product liability and consumer protection laws applied in this case because the design of the platform was by itself a commercial product. “Thus, because Meta has designed a product, placed that product in the stream of commerce, marketed it, and profited from it, Meta has a duty to reasonably design the Social Media Platforms,” Kissinger ruled. The decision also rejected Meta’s argument it was exempt from liability under the federal Communications Decency Act because the suit targets the company’s design of addictive features of its apps and not as a publisher of content. “This ruling is the first step toward holding Meta accountable for its actions in New Hampshire. This is a clear victory for the people of New Hampshire, particularly our children, who are increasingly vulnerable to the addictive and harmful features embedded in social media platforms,” Formella said in a statement. “Meta’s business model thrives by exploiting teenagers’ attention, and today’s decision sends a message that the court will allow the State’s case seeking accountability from the social media giant for its harmful conduct to proceed.” Earlier in 2023, 33 other attorneys general brought a similar joint action against Meta in a California federal court, charging the company with hooking young children on their platforms, which prosecutors maintain has led to higher rates of anxiety, depression and insomnia. New Hampshire, Massachusetts and Vermont are among eight states and the District of Columbia that brought their own suits in state courts. “New Hampshire will not stand by while our children’s mental and emotional health is put at risk for the sake of profit,” Formella added. Meta is the world’s largest social media company. Facebook, WhatsApp and Instagram each has more than a billion users. Last June, the state brought a similar suit against the makers of TikTok, the wildly popular platform that allows users to create, share and distribute short videos. Gov. Chris Sununu said these suits were Formella’s response to the executive order he signed in the spring of 2023 that directed state agencies to develop curriculum aimed at reducing social media harms. klandrigan@unionleader.com

( MENAFN - Live Mint) President-elect Donald trump Donald Trump has nominated Kashyap“Kash” Patel as his pick for FBI Director, signalling a dramatic shift in his approach to the nation's top law enforcement agency. The decision, announced Saturday on Donald Trump's Truth Social platform, aligns with his longstanding goal of restructuring federal agencies and targeting what he perceives as a politicised“deep state.” Donald Trump lauded Patel as a“brilliant lawyer, investigator, and 'America First' fighter,” emphasising Patel's role in exposing alleged misconduct within government agencies.“Kash is a brilliant lawyer, investigator, and 'America First' fighter who has spent his career exposing corruption, defending Justice, and protecting the American People,” Trump declared. (Kash) Patel“played a pivotal role in uncovering the Russia, Russia, Russia Hoax, standing as an advocate for truth, accountability, and the Constitution,” Trump wrote Saturday night. Born to Indian immigrant parents, Kash Patel built his career as a Justice Department prosecutor before joining Capitol Hill as a top staffer on the House Permanent Select Committee on Intelligence. MENAFN30112024007365015876ID1108942144 Legal Disclaimer: MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above.A melee broke out at midfield of Ohio Stadium after Michigan upset No. 2 Ohio State 13-10 on Saturday. After the Wolverines' fourth straight win in the series, players converged at the block "O" to plant its flag. The Ohio State players were in the south end zone singing their alma mater in front of the student section. When the Buckeyes saw the Wolverines' flag, they rushed toward the 50-yard line. Social media posts showed Michigan offensive lineman Raheem Anderson carrying the flag on a long pole to midfield, where the Wolverines were met by dozens of Ohio State players and fights broke out. Buckeyes defensive end Jack Sawyer was seen ripping the flag off the pole and taking the flag as he scuffled with several people trying to recover the flag. A statement from the Ohio State Police Department read: "Following the game, officers from multiple law enforcement agencies assisted in breaking up an on-field altercation. During the scuffle, multiple officers representing Ohio and Michigan deployed pepper spray. OSUPD is the lead agency for games and will continue to investigate." Michigan running back Kalel Mullings on FOX said: "For such a great game, you hate to see stuff like that after the game. It's bad for the sport, bad for college football. At the end of the day, some people got to learn how to lose, man. "You can't be fighting and stuff just because you lost the game. We had 60 minutes and four quarters to do all that fighting. Now people want to talk and fight. That's wrong. It's bad for the game. Classless, in my opinion. People got to be better." Once order was restored, officers cordoned the 50-yard line, using bicycles as barriers. Ohio State coach Ryan Day in his postgame press conference said he wasn't sure what happened. "I don't know all the details of it. But I know that these guys are looking to put a flag on our field and our guys weren't going to let that happen," he said. "I'll find out exactly what happened, but this is our field and certainly we're embarrassed at the fact we lost the game, but there's some prideful guys on our team that weren't just going to let that happen." The Big Ten has not yet released a statement on the incident. --Field Level MediaMUMBAI: After heavy selling, it now appears that foreign institutional investors (FIIs) are likely to turn out consistent buyers when the market corrects further and valuations become attractive, market watchers said on Saturday. A perplexing feature of the recent FII activity is their highly erratic nature. For instance, in the three days from November 23-25, FIIs were buyers. But in the next two days, they again turned sellers, having sold equity for Rs 16,139 crore in the Indian market. "FII selling in November is lower than that of October. In October, the total FII selling through stock exchanges was Rs 113,858 crore. In November, this had come down to Rs 39,315 crore," an expert said. This can be partly attributed to the reduced valuations caused by the correction in the market. Earlier this week, FIIs made a substantial comeback, injecting Rs 11,100 crore into Indian equities over three sessions. This could signal renewed confidence in India's growth story amid global headwinds, providing hope for market stability in the near term, said Vikram Kasat, Head-Advisory, PL Capital-Prabhudas Lilladher. The trend of FII buying through the primary market continues. In November, FIIs bought stocks for Rs 17,704 crores through the primary market. According to experts, if we take the period up to November 29, the total FII selling for the year stands at Rs 118,620 crore. On Friday, the Indian stock market closed in green, as both the equity benchmark indices Sensex and Nifty witnessed a strong rally. Sensex closed at 79,802.79 after a gain of 759.05 points or 0.96 per cent. Nifty closed at 24,131.10 after a gain of 216.95 points or 0.91 per cent. The domestic stock market increased due to better investor sentiment and stock-specific activities. According to experts, "a large-cap-driven, broad-based rally ensued in the domestic market. Discretionary sectors performed well, benefiting from the festive season". Technically, the market remains in a consolidation phase, with little change in chart structure. "Traders are advised to avoid aggressive bets and be selective. It’s also crucial to monitor global factors closely, as they could influence market direction ahead of the weekly expiry," said Rajesh Bhosale, equity technical analyst, Angel One.

Closing marks second significant acquisition from RA Capital's Raven incubator in 2024, and first acquisition of a company built by Raven from a technology platform in-licensed from a large pharmaceutical company BOSTON , Dec. 11, 2024 /PRNewswire/ -- RA Capital Management, LP (RA Capital), a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies, today announced that AbbVie has closed its $1.4 billion acquisition of RA Capital's portfolio company Aliada Therapeutics. Aliada's lead investigational asset is ALIA-1758, an anti-pyroglutamate amyloid beta (3pE-Aβ) antibody, which is in development for the treatment of Alzheimer's disease and is currently in a Phase 1 clinical trial. ALIA-1758 utilizes a novel blood-brain barrier-crossing technology that enhances delivery of targeted drugs into the central nervous system. Johnson & Johnson (through its venture capital arm, Johnson & Johnson Innovation – JJDC, Inc.), RA Capital, and Raven (RA Capital's healthcare incubator) co-founded Aliada and co-led the series seed financing in 2021 to advance the MODELTM platform created by Johnson & Johnson scientists that was licensed to Aliada at its inception. "Congratulations to the Aliada and AbbVie teams and our fellow investors on the close of this transaction," said Joshua Resnick , MD, Senior Managing Director at RA Capital Management and former board director at Aliada. "The acquisition of Aliada is the second significant acquisition of a Raven-grown company this year, joining Novartis' $1 billion upfront acquisition of radiopharmaceutical developer Mariana Oncology in May." "Delivering therapeutics across the blood-brain barrier with a low-volume, subcutaneous injection would be revolutionary for treating Alzheimer's disease and other neurological disorders, and has long been a dream in the field," said Laura Tadvalkar , PhD, Managing Director at RA Capital Management and former board chair at Aliada. "We look forward to following ALIA-1758's progress through the clinic, as AbbVie advances this important medicine for Alzheimer's disease patients." About Raven Raven is RA Capital Management's healthcare incubator. Raven's experienced team of scientists, operators, and innovators bring deep sector expertise, insight and executional capabilities across therapeutics, diagnostics, devices, and services. Raven builds companies: from originating and incubating new ideas to accelerating compelling innovations and rejuvenating promising assets. About RA Capital Founded in 2004, RA Capital Management is a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies. RA Capital creates and funds innovative companies, from private seed rounds to public follow-on financings, allowing management teams to drive value creation from inception through commercialization and beyond. RA Capital's knowledge engine is guided by our TechAtlas internal research division, and Raven, RA Capital's company creation team, offers entrepreneurs and innovators a collaborative and comprehensive platform to explore the novel and the re-imagined. RA Capital has more than 175 employees and over $10 billion in assets under management. The companies presented herein were selected to demonstrate a potential successful outcome of a company being incubated within our Raven incubator. They are not intended to represent a complete picture of RA Capital's portfolio, its exposures, risks or potential for positive or negative returns. Past performance is not indicative of future results. View original content to download multimedia: https://www.prnewswire.com/news-releases/ra-capital-management-announces-close-of-1-4-billion-acquisition-of-aliada-therapeutics-by-abbvie-302329567.html SOURCE RA Capital Management, LP

Tulane QB Mensah transfers to Duke

Advertisement A mother uses holiday traditions to connect her children with their family history. She shares stories, photos, and heirlooms to keep memories of past generations alive. Family gatherings, food, and music help bridge the gap between past and present. The holidays have always been important to me and my family. Growing up, my grandparents and foster mother made sure that November and December were filled with parties and events that both exhausted our family and filled us with joy. I still think fondly of these times and draw on them for inspiration as I'm working to create new memories with my kids , ages 19, 18, 13, and 11. In addition to being fun, passing along old traditions and sharing memories has helped me as I've grieved the shrinking of the family I grew up with. Telling cherished stories helps keep memories alive. Advertisement For example, my foster mother, Esther, and her three biological children, who I came to know as my sisters and brother, had a fake cardboard fireplace we'd line with stockings every year. I now relay this story to my kids in front of our real fireplace as we decorate our tree. It helps them to get to know a bit about my humble beginnings and about the creativity of a woman they never had the chance to meet. Here are other ways I help keep holiday traditions and the spirit of the past alive each year. Related stories Curating a home full of history I decorate our home with many holiday items my grandmother passed down to me. There are the marshmallow-white snowball people, a favorite of hers, that I now display on my bookshelf. My Christmas tree is covered with ornaments from the 1960s through today. When my children and I unwrap these mementos each year, I recall moments from when I was a kid and share those stories with them. Now, I buy each of my children their own special ornament each year to remind them of our family and this time we're spending together. One day, they will have their own collection of ornaments and stories to pass down. Advertisement Photos help keep memories top-of-mind The holidays have always been about family. But many of the people who made my holiday celebrations so magical are gone now. To remember them, I share pictures with my kids. I have five albums filled with memories of Christmases past, and we look at them every year. One favorite snapshot shows our family singing along with Mitch Miller, the famous composer we listened to every Christmas on the old record player. This annual gathering was organized by my aunt, who dressed in silly holiday hats and sweaters. Another image shows one of the last Christmases we'd celebrate with Gram and Gramps. There are also pictures of me visiting Santa at the mall. I share these images to connect my children to people they knew briefly or not at all. These people are a part of who I am and are woven into the fabric of who my children will become. Coming together over food is a favorite pastime My Italian family treasured food, and the time we shared creating meals — especially around the holidays. I fondly recall my aunts and grandmother gathered in the kitchen and exchanging stories, while preparing our favorite dishes. For big holidays, we now set the dining room table, which I inherited from my grandparents, with the Noritake china my grandmother also passed down to me. The delicate flowers dancing along the dishes' edges remind me of holiday dinners with her. Even more of her cherished trinkets decorate the dining room, helping to make it feel like she is there with us as we eat our Thanksgiving and Christmas dinners. Advertisement In the kitchen on Christmas Eve, we have a tradition of baking Italian cookies like the ones my great-grandmother used to make. They never taste exactly like Grams. But what they lack in authenticity, they make up for with the memories they bring. The author and her children decorate their Christmas tree with ornaments from past generations each year. Nicole Johnson A party brings it all together For years we have hosted our own Christmas party, a homage to the parties of my youth. Now, they have become a tradition I've created with and for my family. We invite friends and family — sometimes as many as 100 people. We cook too much food and have even welcomed special visitors like Santa through the years. I play music by Elvis, Frank Sinatra, Burl Ives, Bing Crosby, and Johnny Mathis, making sure my kids know these classic carols were my grandmother's favorites. Sharing these traditions allows me to give my kids a glimpse of my past. I have transitioned from one family to another, but I still remember where I came from and make sure my kids will do the same one day. I have fostered relationships that would have otherwise disappeared, making the holidays a time we look forward to each year and reminding my kids that the true meaning of these special days is family.SF psychedelic church dedicated to psilocybin mushrooms to close, cites harassment from cityNone

lottery prediction
lottery prediction 7 Things You Probably Didn’t Know About KimonoMonopar Announces First Patient Dosed with its Novel Therapeutic Radiopharmaceutical MNPR-101-LuRuben Amorim says he 'truly believes' Man Utd can win the Premier League

Assad's fall leaves Syria's future uncertainCalifornia politicians suddenly discover inflation in aftermath of election

Infinix Empowers Gamers as Official Gaming Phone for 2024 PMGC

The NFL said on Friday that its Week 16 game between AFC West rivals Denver Broncos and Los Angeles Chargers , both firmly in the hunt for a postseason berth, has been moved up in the schedule to be that week’s Thursday Night Football game on Prime Video . The game, at SoFi Stadium in Inglewood, will now kick off at 8:15 p.m. ET/5:15 p.m. PT on December 19. The move means the regularly scheduled TNF game that week, Cleveland at Cincinnati, will now be played Sunday, December 12 at 1 p.m. ET and air on Fox. The Chargers (7-3) under new coach Jim Harbaugh have won four games in a row heading into a Monday Night Football showdown at home against the Baltimore Ravens (8:15 p.m. ET, ABC/ESPN). Denver (6-5), plays the Las Vegas Raiders on the road Sunday. The NFL has had a deal with the networks about tweaking its schedule to ensure strong matchups and give teams a chance to play their way onto primetime schedules. Originally implemented for NBC’s Sunday Night Football programming, the flex can also be implemented for Monday Night Football , as well as TNF on a trial basis beginning this season. Amazon’s Prime Video has seen success with its TNF programming as fans become more accustomed to streaming services to find games. This is the third year of TNF on Prime Video; the schedule features 15 regular-season games including a Black Friday game pitting the Kansas City Chiefs and Raiders next week, in addition to a wild-card playoff game in January. Another streamer, Netflix, is making inroads with the NFL as well this season hosting a pair of games live on Christmas Day.

Panama president rules out talks with Trump over canal threatA Merrimack County Superior Court judge delivered an early-but-significant victory to Attorney General John Formella’s sweeping lawsuit that accuses Meta, the parent company of Facebook, Instagram and WhatsApp, of using marketing methods that mentally and physically harm young children. Lawyers for Meta had moved to dismiss the suit Formella brought last October, but denial of that motion means the five-count claim will go forward. Judge John Kissinger cited the clout of these platforms in making a critical finding that the state has “sovereign interest” and jurisdiction over Meta’s designs due to the potential impact on the mental health of young people. “13.49% of the under-eighteen population are active monthly Facebook users and 35% are active monthly Instagram users,” Kissinger wrote in a detailed 56-page ruling. “Teenagers in New Hampshire have also suffered from declining mental health since 2011. The state has an interest in protecting the mental health of its youngest population. The court sees no reason to distinguish between physical and mental health in this context.” In another key decision, Kissinger said the First Amendment gave Meta no immunity from lawsuit because the state was targeting the design of the platform and not the specific content on social media. He also decided that the product liability and consumer protection laws applied in this case because the design of the platform was by itself a commercial product. “Thus, because Meta has designed a product, placed that product in the stream of commerce, marketed it, and profited from it, Meta has a duty to reasonably design the Social Media Platforms,” Kissinger ruled. The decision also rejected Meta’s argument it was exempt from liability under the federal Communications Decency Act because the suit targets the company’s design of addictive features of its apps and not as a publisher of content. “This ruling is the first step toward holding Meta accountable for its actions in New Hampshire. This is a clear victory for the people of New Hampshire, particularly our children, who are increasingly vulnerable to the addictive and harmful features embedded in social media platforms,” Formella said in a statement. “Meta’s business model thrives by exploiting teenagers’ attention, and today’s decision sends a message that the court will allow the State’s case seeking accountability from the social media giant for its harmful conduct to proceed.” Earlier in 2023, 33 other attorneys general brought a similar joint action against Meta in a California federal court, charging the company with hooking young children on their platforms, which prosecutors maintain has led to higher rates of anxiety, depression and insomnia. New Hampshire, Massachusetts and Vermont are among eight states and the District of Columbia that brought their own suits in state courts. “New Hampshire will not stand by while our children’s mental and emotional health is put at risk for the sake of profit,” Formella added. Meta is the world’s largest social media company. Facebook, WhatsApp and Instagram each has more than a billion users. Last June, the state brought a similar suit against the makers of TikTok, the wildly popular platform that allows users to create, share and distribute short videos. Gov. Chris Sununu said these suits were Formella’s response to the executive order he signed in the spring of 2023 that directed state agencies to develop curriculum aimed at reducing social media harms. klandrigan@unionleader.com

( MENAFN - Live Mint) President-elect Donald trump Donald Trump has nominated Kashyap“Kash” Patel as his pick for FBI Director, signalling a dramatic shift in his approach to the nation's top law enforcement agency. The decision, announced Saturday on Donald Trump's Truth Social platform, aligns with his longstanding goal of restructuring federal agencies and targeting what he perceives as a politicised“deep state.” Donald Trump lauded Patel as a“brilliant lawyer, investigator, and 'America First' fighter,” emphasising Patel's role in exposing alleged misconduct within government agencies.“Kash is a brilliant lawyer, investigator, and 'America First' fighter who has spent his career exposing corruption, defending Justice, and protecting the American People,” Trump declared. (Kash) Patel“played a pivotal role in uncovering the Russia, Russia, Russia Hoax, standing as an advocate for truth, accountability, and the Constitution,” Trump wrote Saturday night. Born to Indian immigrant parents, Kash Patel built his career as a Justice Department prosecutor before joining Capitol Hill as a top staffer on the House Permanent Select Committee on Intelligence. MENAFN30112024007365015876ID1108942144 Legal Disclaimer: MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above.A melee broke out at midfield of Ohio Stadium after Michigan upset No. 2 Ohio State 13-10 on Saturday. After the Wolverines' fourth straight win in the series, players converged at the block "O" to plant its flag. The Ohio State players were in the south end zone singing their alma mater in front of the student section. When the Buckeyes saw the Wolverines' flag, they rushed toward the 50-yard line. Social media posts showed Michigan offensive lineman Raheem Anderson carrying the flag on a long pole to midfield, where the Wolverines were met by dozens of Ohio State players and fights broke out. Buckeyes defensive end Jack Sawyer was seen ripping the flag off the pole and taking the flag as he scuffled with several people trying to recover the flag. A statement from the Ohio State Police Department read: "Following the game, officers from multiple law enforcement agencies assisted in breaking up an on-field altercation. During the scuffle, multiple officers representing Ohio and Michigan deployed pepper spray. OSUPD is the lead agency for games and will continue to investigate." Michigan running back Kalel Mullings on FOX said: "For such a great game, you hate to see stuff like that after the game. It's bad for the sport, bad for college football. At the end of the day, some people got to learn how to lose, man. "You can't be fighting and stuff just because you lost the game. We had 60 minutes and four quarters to do all that fighting. Now people want to talk and fight. That's wrong. It's bad for the game. Classless, in my opinion. People got to be better." Once order was restored, officers cordoned the 50-yard line, using bicycles as barriers. Ohio State coach Ryan Day in his postgame press conference said he wasn't sure what happened. "I don't know all the details of it. But I know that these guys are looking to put a flag on our field and our guys weren't going to let that happen," he said. "I'll find out exactly what happened, but this is our field and certainly we're embarrassed at the fact we lost the game, but there's some prideful guys on our team that weren't just going to let that happen." The Big Ten has not yet released a statement on the incident. --Field Level MediaMUMBAI: After heavy selling, it now appears that foreign institutional investors (FIIs) are likely to turn out consistent buyers when the market corrects further and valuations become attractive, market watchers said on Saturday. A perplexing feature of the recent FII activity is their highly erratic nature. For instance, in the three days from November 23-25, FIIs were buyers. But in the next two days, they again turned sellers, having sold equity for Rs 16,139 crore in the Indian market. "FII selling in November is lower than that of October. In October, the total FII selling through stock exchanges was Rs 113,858 crore. In November, this had come down to Rs 39,315 crore," an expert said. This can be partly attributed to the reduced valuations caused by the correction in the market. Earlier this week, FIIs made a substantial comeback, injecting Rs 11,100 crore into Indian equities over three sessions. This could signal renewed confidence in India's growth story amid global headwinds, providing hope for market stability in the near term, said Vikram Kasat, Head-Advisory, PL Capital-Prabhudas Lilladher. The trend of FII buying through the primary market continues. In November, FIIs bought stocks for Rs 17,704 crores through the primary market. According to experts, if we take the period up to November 29, the total FII selling for the year stands at Rs 118,620 crore. On Friday, the Indian stock market closed in green, as both the equity benchmark indices Sensex and Nifty witnessed a strong rally. Sensex closed at 79,802.79 after a gain of 759.05 points or 0.96 per cent. Nifty closed at 24,131.10 after a gain of 216.95 points or 0.91 per cent. The domestic stock market increased due to better investor sentiment and stock-specific activities. According to experts, "a large-cap-driven, broad-based rally ensued in the domestic market. Discretionary sectors performed well, benefiting from the festive season". Technically, the market remains in a consolidation phase, with little change in chart structure. "Traders are advised to avoid aggressive bets and be selective. It’s also crucial to monitor global factors closely, as they could influence market direction ahead of the weekly expiry," said Rajesh Bhosale, equity technical analyst, Angel One.

Closing marks second significant acquisition from RA Capital's Raven incubator in 2024, and first acquisition of a company built by Raven from a technology platform in-licensed from a large pharmaceutical company BOSTON , Dec. 11, 2024 /PRNewswire/ -- RA Capital Management, LP (RA Capital), a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies, today announced that AbbVie has closed its $1.4 billion acquisition of RA Capital's portfolio company Aliada Therapeutics. Aliada's lead investigational asset is ALIA-1758, an anti-pyroglutamate amyloid beta (3pE-Aβ) antibody, which is in development for the treatment of Alzheimer's disease and is currently in a Phase 1 clinical trial. ALIA-1758 utilizes a novel blood-brain barrier-crossing technology that enhances delivery of targeted drugs into the central nervous system. Johnson & Johnson (through its venture capital arm, Johnson & Johnson Innovation – JJDC, Inc.), RA Capital, and Raven (RA Capital's healthcare incubator) co-founded Aliada and co-led the series seed financing in 2021 to advance the MODELTM platform created by Johnson & Johnson scientists that was licensed to Aliada at its inception. "Congratulations to the Aliada and AbbVie teams and our fellow investors on the close of this transaction," said Joshua Resnick , MD, Senior Managing Director at RA Capital Management and former board director at Aliada. "The acquisition of Aliada is the second significant acquisition of a Raven-grown company this year, joining Novartis' $1 billion upfront acquisition of radiopharmaceutical developer Mariana Oncology in May." "Delivering therapeutics across the blood-brain barrier with a low-volume, subcutaneous injection would be revolutionary for treating Alzheimer's disease and other neurological disorders, and has long been a dream in the field," said Laura Tadvalkar , PhD, Managing Director at RA Capital Management and former board chair at Aliada. "We look forward to following ALIA-1758's progress through the clinic, as AbbVie advances this important medicine for Alzheimer's disease patients." About Raven Raven is RA Capital Management's healthcare incubator. Raven's experienced team of scientists, operators, and innovators bring deep sector expertise, insight and executional capabilities across therapeutics, diagnostics, devices, and services. Raven builds companies: from originating and incubating new ideas to accelerating compelling innovations and rejuvenating promising assets. About RA Capital Founded in 2004, RA Capital Management is a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies. RA Capital creates and funds innovative companies, from private seed rounds to public follow-on financings, allowing management teams to drive value creation from inception through commercialization and beyond. RA Capital's knowledge engine is guided by our TechAtlas internal research division, and Raven, RA Capital's company creation team, offers entrepreneurs and innovators a collaborative and comprehensive platform to explore the novel and the re-imagined. RA Capital has more than 175 employees and over $10 billion in assets under management. The companies presented herein were selected to demonstrate a potential successful outcome of a company being incubated within our Raven incubator. They are not intended to represent a complete picture of RA Capital's portfolio, its exposures, risks or potential for positive or negative returns. Past performance is not indicative of future results. View original content to download multimedia: https://www.prnewswire.com/news-releases/ra-capital-management-announces-close-of-1-4-billion-acquisition-of-aliada-therapeutics-by-abbvie-302329567.html SOURCE RA Capital Management, LP

Tulane QB Mensah transfers to Duke

Advertisement A mother uses holiday traditions to connect her children with their family history. She shares stories, photos, and heirlooms to keep memories of past generations alive. Family gatherings, food, and music help bridge the gap between past and present. The holidays have always been important to me and my family. Growing up, my grandparents and foster mother made sure that November and December were filled with parties and events that both exhausted our family and filled us with joy. I still think fondly of these times and draw on them for inspiration as I'm working to create new memories with my kids , ages 19, 18, 13, and 11. In addition to being fun, passing along old traditions and sharing memories has helped me as I've grieved the shrinking of the family I grew up with. Telling cherished stories helps keep memories alive. Advertisement For example, my foster mother, Esther, and her three biological children, who I came to know as my sisters and brother, had a fake cardboard fireplace we'd line with stockings every year. I now relay this story to my kids in front of our real fireplace as we decorate our tree. It helps them to get to know a bit about my humble beginnings and about the creativity of a woman they never had the chance to meet. Here are other ways I help keep holiday traditions and the spirit of the past alive each year. Related stories Curating a home full of history I decorate our home with many holiday items my grandmother passed down to me. There are the marshmallow-white snowball people, a favorite of hers, that I now display on my bookshelf. My Christmas tree is covered with ornaments from the 1960s through today. When my children and I unwrap these mementos each year, I recall moments from when I was a kid and share those stories with them. Now, I buy each of my children their own special ornament each year to remind them of our family and this time we're spending together. One day, they will have their own collection of ornaments and stories to pass down. Advertisement Photos help keep memories top-of-mind The holidays have always been about family. But many of the people who made my holiday celebrations so magical are gone now. To remember them, I share pictures with my kids. I have five albums filled with memories of Christmases past, and we look at them every year. One favorite snapshot shows our family singing along with Mitch Miller, the famous composer we listened to every Christmas on the old record player. This annual gathering was organized by my aunt, who dressed in silly holiday hats and sweaters. Another image shows one of the last Christmases we'd celebrate with Gram and Gramps. There are also pictures of me visiting Santa at the mall. I share these images to connect my children to people they knew briefly or not at all. These people are a part of who I am and are woven into the fabric of who my children will become. Coming together over food is a favorite pastime My Italian family treasured food, and the time we shared creating meals — especially around the holidays. I fondly recall my aunts and grandmother gathered in the kitchen and exchanging stories, while preparing our favorite dishes. For big holidays, we now set the dining room table, which I inherited from my grandparents, with the Noritake china my grandmother also passed down to me. The delicate flowers dancing along the dishes' edges remind me of holiday dinners with her. Even more of her cherished trinkets decorate the dining room, helping to make it feel like she is there with us as we eat our Thanksgiving and Christmas dinners. Advertisement In the kitchen on Christmas Eve, we have a tradition of baking Italian cookies like the ones my great-grandmother used to make. They never taste exactly like Grams. But what they lack in authenticity, they make up for with the memories they bring. The author and her children decorate their Christmas tree with ornaments from past generations each year. Nicole Johnson A party brings it all together For years we have hosted our own Christmas party, a homage to the parties of my youth. Now, they have become a tradition I've created with and for my family. We invite friends and family — sometimes as many as 100 people. We cook too much food and have even welcomed special visitors like Santa through the years. I play music by Elvis, Frank Sinatra, Burl Ives, Bing Crosby, and Johnny Mathis, making sure my kids know these classic carols were my grandmother's favorites. Sharing these traditions allows me to give my kids a glimpse of my past. I have transitioned from one family to another, but I still remember where I came from and make sure my kids will do the same one day. I have fostered relationships that would have otherwise disappeared, making the holidays a time we look forward to each year and reminding my kids that the true meaning of these special days is family.SF psychedelic church dedicated to psilocybin mushrooms to close, cites harassment from cityNone

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